Evidence map›Paper›PMID 26931327›Full record

ReviewCold Spring Harbor perspectives in biology2016

Detection and Phenotypic Characterization of Adult Neurogenesis.

H Georg Kuhn, Amelia J Eisch, Kirsty Spalding, Daniel A Peterson

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Article
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  7. Effects of crocin on the enhancement ofIranian journal of basic medical sciences · 2024
    Article
  8. Article
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  13. Review
  14. Direct FACS Isolation of Neural Stem/Progenitor Lineages from the Adult Brain.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  15. Article
  16. Article
  17. Review
  18. Deltamethrin Exposure Inhibits Adult Hippocampal Neurogenesis and Causes Deficits in Learning and Memory in Mice.Toxicological sciences : an official journal of the Society of Toxicology · 2020
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

H Georg KuhnInstitute for Neuroscience and Physiology, University of Gothenburg, Gothenburg, SE-405 30, Sweden.
Amelia J EischDepartment of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9070.
Kirsty SpaldingDepartment of Cell and Molecular Biology, Karolinska Institute, Stockholm SE-171 77, Sweden.
Daniel A PetersonCenter for Stem Cell and Regenerative Medicine, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064.

Funding

New Horizons in Adult NeurogenesisK02DA023555 · NIDA · UT SOUTHWESTERN MEDICAL CENTER · PI EISCH, AMELIA J · 2007 to 2017
$1.1M
NIDA NIH HHS K02 DA023555
6 · The paper itself

Abstract

Studies of adult neurogenesis have greatly expanded in the last decade, largely as a result of improved tools for detecting and quantifying neurogenesis. In this review, we summarize and critically evaluate detection methods for neurogenesis in mammalian and human brain tissue. Besides thymidine analog labeling, cell-cycle markers are discussed, as well as cell stage and lineage commitment markers. Use of these histological tools is critically evaluated in terms of their strengths and limitations, as well as possible artifacts. Finally, we discuss the method of radiocarbon dating for determining cell and tissue turnover in humans.

Indexed as

NeurogenesisAge FactorsBiomarkersCell CycleCell Cycle ProteinsCell LineageGenetic VectorsHumansNeural Stem CellsPhenotypeRadiometric DatingStaining and LabelingThymidineBiomarkersCell Cycle ProteinsThymidine

Identifiers

PMID26931327
PMCPMC4772100

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.