Evidence map›Paper›PMID 26931145›Full record

ReviewEuropean journal of medical research2016

Total hip arthroplasty-related osteogenic osteosarcoma: case report and review of the literature.

Rajko Kavalar, Samo K Fokter, Janez Lamovec

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in European journal of medical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Resorbable MgMaterials (Basel, Switzerland) · 2021
    Review
  7. Review
  8. Article
  9. Osteosarcoma of the proximal tibia in a dog 6 years after tibial tuberosity advancement.The Canadian veterinary journal = La revue veterinaire canadienne · 2020
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Rajko KavalarDepartment of Pathology, University Medical Centre Maribor, Ljubljanska ulica 5, 2000, Maribor, Slovenia. rajko.kavalar@gmail.com.
Samo K FokterDepartment of Orthopedics, University Medical Centre Maribor, Maribor, Slovenia. samo.fokter@guest.arnes.si.
Janez LamovecDepartment of Pathology, Institute of Oncology, Ljubljana, Slovenia. jlamovec@onko-i.si.
University Clinical Centre Maribor · SIInstitute of Oncology Ljubljana · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOrthopedic implant-related sarcoma is an exceedingly rare, but a known complication of total hip arthroplasty (THA). CASE PRESENTATION: The authors describe clinical and radiologic features, histologic appearance, and treatment of osteogenic osteosarcoma located in the proximal femoral diaphysis associated with an unstable femoral prosthesis following THA in a 65-year-old male patient. The patient with HLA-B27 positive ankylosing spondylitis underwent arthroplasty 15 years ago.

conclusionsThe neoplastic process may be considered as an extraordinary complication of THA and might just be coincidental or the result of some derangement of the healing process in host tissue with no definitely proven hypothesis that the implants or their by-products are carcinogenic. The soluble chemical substances from the implanted prosthetic material are, at least in animals, suspected to play a vital role in the pathogenesis of the neoplastic transformation of the bone tissue. The presented case shall alert orthopedic surgeons to clinical, radiologic, and macroscopic similarities between a malignant tumor and benign lesions caused by wear debris at THA sites. At the examination of plane X-rays of patients with THA loosening, the differential diagnosis should always include osteogenic sarcoma, as well. To our knowledge, there have been only nine cases of THA-related osteogenic osteosarcomas described in the English-language literature.

Indexed as

AgedArthroplasty, Replacement, HipBone NeoplasmsDiagnosis, DifferentialDiaphysesFemurHLA-B27 AntigenHumansMaleOsteosarcomaPostoperative ComplicationsRadiographySpondylitis, AnkylosingHLA-B27 Antigen

Identifiers

PMID26931145
PMCPMC4774038
OpenAlexW2292438439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.