Evidence map›Paper›PMID 26930385›Full record

ReviewJournal of comparative effectiveness research2016

Improving the relevance and consistency of outcomes in comparative effectiveness research.

Sean R Tunis, Mike Clarke, Sarah L Gorst, Elizabeth Gargon, Jane M Blazeby, Douglas G Altman, Paula R Williamson

Abstract readReview
In one paragraph

Review in Journal of comparative effectiveness research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Pooled it
  2. Ginkgo biloba for tinnitus.The Cochrane database of systematic reviews · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sean R TunisCenter for Medical Technology Policy, Baltimore, MD 21202, USA.
Mike ClarkeCentre for Public Health, Queen's University Belfast, Belfast, UK.
Sarah L GorstDepartment of Biostatistics, University of Liverpool, Liverpool, UK.
Elizabeth GargonDepartment of Biostatistics, University of Liverpool, Liverpool, UK.
Jane M BlazebySchool of Social & Community Medicine, University of Bristol, Bristol, UK.
Douglas G AltmanCentre for Statistics in Medicine, University of Oxford, Oxford, UK.
Paula R WilliamsonDepartment of Biostatistics, University of Liverpool, Liverpool, UK.

Funding

Cancer Research UK 16895Medical Research Council G0901530Medical Research Council MR/J004847/1
6 · The paper itself

Abstract

Policy makers have clearly indicated--through heavy investment in the Patient Centered Outcomes Research Institute--that reporting outcomes that are meaningful to patients is crucial for improvement in healthcare delivery and cost reduction. Better interpretation and generalizability of clinical research results that incorporate patient-centered outcomes research can be achieved by accelerating the development and uptake of core outcome sets (COS). COS provide a standardized minimum set of the outcomes that should be measured and reported in all clinical trials of a specific condition. The level of activity around COS has increased significantly over the past decade, with substantial progress in several clinical domains. However, there are many important clinical conditions for which high-quality COS have not been developed and there are limited resources and capacity with which to develop them. We believe that meaningful progress toward the goals behind the significant investments in patient-centered outcomes research and comparative effectiveness research will depend on a serious effort to address these issues.

Indexed as

Delivery of Health CareResearch DesignComparative Effectiveness ResearchHumansOutcome Assessment, Health Careclinical trialsclinician-reported outcomescomparative effectivenesspatient-centered outcomespatient-reported outcomesquality of lifereimbursement scienceresearch methodsresearch standardsresearch waste

Identifiers

PMID26930385
PMCPMC4926524

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.