Evidence map›Paper›PMID 26930352›Full record

ArticlePloS one2016

The Transmission and Antibiotic Resistance Variation in a Multiple Drug Resistance Clade of Vibrio cholerae Circulating in Multiple Countries in Asia.

Bo Pang, Pengcheng Du, Zhemin Zhou, Baowei Diao, Zhigang Cui, Haijian Zhou, Biao Kan

Abstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bo PangNational Institute for Communicable Disease Control and Prevention, China CDC, Beijing, 102206, People's Republic of China.
Pengcheng DuBeijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, 100015, People's Republic of China.
Zhemin ZhouWarwick Medical School, University of Warwick, Coventry, CV4 7AL, United Kingdom.
Baowei DiaoNational Institute for Communicable Disease Control and Prevention, China CDC, Beijing, 102206, People's Republic of China.
Zhigang CuiNational Institute for Communicable Disease Control and Prevention, China CDC, Beijing, 102206, People's Republic of China.
Haijian ZhouNational Institute for Communicable Disease Control and Prevention, China CDC, Beijing, 102206, People's Republic of China.
Biao KanNational Institute for Communicable Disease Control and Prevention, China CDC, Beijing, 102206, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vibrio cholerae has caused massive outbreaks and even trans-continental epidemics. In 2008 and 2010, at least 3 remarkable cholera outbreaks occurred in Hainan, Anhui and Jiangsu provinces of China. To address the possible transmissions and the relationships to the 7th pandemic strains of those 3 outbreaks, we sequenced the whole genomes of the outbreak isolates and compared with the global isolates from the 7th pandemic. The three outbreaks in this study were caused by a cluster of V. cholerae in clade 3.B which is parallel to the clade 3.C that was transmitted from Nepal to Haiti and caused an outbreak in 2010. Pan-genome analysis provided additional evolution information on the mobile element and acquired multiple antibiotic resistance genes. We suggested that clade 3.B should be monitored because the multiple antibiotic resistant characteristics of this clade and the 'amplifier' function of China in the global transmission of current Cholera pandemic. We also show that dedicated whole genome sequencing analysis provided more information than the previous techniques and should be applied in the disease surveillance networks.

Indexed as

Anti-Bacterial AgentsAsiaCholeraDisease OutbreaksDrug Resistance, MicrobialDrug Resistance, MultipleEpidemicsGenetic VariationGenome, BacterialPhylogenySequence Analysis, DNAVibrio choleraeAnti-Bacterial Agents

Identifiers

PMID26930352
PMCPMC4773069

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.