ArticleWorld journal of experimental medicine2016
Inflammatory diseases modelling in zebrafish.
Article in World journal of experimental medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 27 citations in OpenAlex.
- Anti-inflammatory and protective effects of Aloe vera on intestinal function in zebrafish.Journal of molecular histology · 2026Article
- Comparison of the Gut Microbial Communities of Domestic and Wild Mallards (Animals : an open access journal from MDPI · 2023Article
- Dietary Strategies to Modulate the Health Condition and Immune Responses in Gilthead Seabream (Animals : an open access journal from MDPI · 2022Article
- Chicken jejunal microbiota improves growth performance by mitigating intestinal inflammation.Microbiome · 2022Article
- Short chain fatty acids (SCFAs) improves TNBS-induced colitis in zebrafish.Current research in immunology · 2021Article
- Articaine in functional NLC show improved anesthesia and anti-inflammatory activity in zebrafish.Scientific reports · 2020Article
- Anti-Inflammatory Activity of Exopolysaccharides fromBiomolecules · 2020Article
- Cholinergic System and Oxidative Stress Changes in the Brain of a Zebrafish Model Chronically Exposed to Ethanol.Neurotoxicity research · 2018Article
- Immunomodulatory effects of excretory/secretory compounds from Contracaecum osculatum larvae in a zebrafish inflammation model.PloS one · 2017Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ingest of diets with high content of fats and carbohydrates, low or no physical exercise and a stressful routine are part of the everyday lifestyle of most people in the western world. These conditions are triggers for different diseases with complex interactions between the host genetics, the metabolism, the immune system and the microbiota, including inflammatory bowel diseases (IBD), obesity and diabetes. The incidence of these disorders is growing worldwide; therefore, new strategies for its study are needed. Nowadays, the majority of researches are in use of murine models for understand the genetics, physiopathology and interaction between cells and signaling pathways to find therapeutic solutions to these diseases. The zebrafish, a little tropical water fish, shares 70% of our genes and conserves anatomic and physiological characteristics, as well as metabolical pathways, with mammals, and is rising as a new complementary model for the study of metabolic and inflammatory diseases. Its high fecundity, fast development, transparency, versatility and low cost of maintenance makes the zebrafish an interesting option for new researches. In this review, we offer a discussion of the existing genetic and induced zebrafish models of two important Western diseases that have a strong inflammatory component, the IBD and the obesity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.