Evidence map›Paper›PMID 26929859›Full record

ArticleAJP reports2016

Comparison of Presentation, Course, and Outcome of Congenital and Acquired Cytomegalovirus Infection in Twins.

Veronica Mugarab Samedi, Christopher Skappak, Lindsay Jantzie, Cynthia Trevenen, Majeeda Kamaluddeen, Pauline Ekwalanga, Essa Hamdan Al Awad

Open access · goldAbstract readCase Reports
In one paragraph

Article in AJP reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Vertical Transmission and Discordance of Cytomegalovirus in Twin Pregnancies.Frontiers in cellular and infection microbiology · 2021
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Veronica Mugarab SamediSection of Neonatology, University of Calgary, Alberta, Calgary, Canada.
Christopher SkappakDepartment of Family Medicine, University of Calgary, Alberta, Calgary, Canada.
Lindsay JantzieDepartment of Family Medicine, University of Calgary, Alberta, Calgary, Canada.
Cynthia TrevenenDepartment of Pathology and Laboratory Medicine, University of Calgary, Alberta, Calgary, Canada.
Majeeda KamaluddeenSection of Neonatology, University of Calgary, Alberta, Calgary, Canada.
Pauline EkwalangaDepartment of Obstetrics and Gynecology, University of Calgary, Alberta, Calgary, Canada.
Essa Hamdan Al AwadSection of Neonatology, University of Calgary, Alberta, Calgary, Canada.
University of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Cytomegalovirus (CMV) is one of the most common causes of serious viral intrauterine infections. It is universally distributed among the human population with an average incidence of 0.15 to 2%. Indeed, at least half of the women in the reproductive age have evidence of prior CMV infection. Epidemiology and Pathogenicity However, it is not a usual practice to screen asymptomatic pregnant woman or neonates for CMV. Even if a mother developed a primary CMV infection during pregnancy, up to 90% of the newborns with congenital CMV will be asymptomatic at the time of birth. Only 5 to 7% of the infected babies will be acutely symptomatic, and the typical clinical presentation includes intrauterine growth restriction, microcephaly, various cutaneous manifestations (including petechiae and purpura), hematological abnormalities (particularly resistant thrombocytopenia), hepatosplenomegaly, chorioretinitis, hepatitis, etc. In contrast, acquired CMV infection is extremely unlikely to cause any serious sequelae for the infant. Cases  We present a case of congenital and acquired CMV infection in twins with a focus of dissimilarity in presentation, clinical course, and outcome.

Indexed as

acquired CMVcholestasiscongenital CMVcytogamintracranial cystsomega-vanthrombocytopeniatwins

Identifiers

PMID26929859
PMCPMC4737621
OpenAlexW2278916298

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.