ReviewClinics in colon and rectal surgery2016
Anal Fissure.
Review in Clinics in colon and rectal surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 6 syntheses or guidelines pooled it, 97 citations in OpenAlex.
- Comparative Efficacy and Safety of Botulinum Toxin and Nitroglycerin in the Treatment of Chronic Anal Fissures: A Systematic Review and Meta-Analysis of Clinical Trials.BioMed research international · 2026Pooled it
- Efficacy and safety of topical vs. oral calcium channel blockers for chronic anal fissures: a systematic review and meta-analysis.Frontiers in pharmacology · 2025Pooled it
- Comparing closed versus open lateral internal sphincterotomy for management of chronic anal fissure: systematic review and meta-analysis of randomised control trials.Scientific reports · 2023Pooled it
- The role of percutaneous tibial nerve stimulation (PTNS) in the treatment of chronic anal fissure: a systematic review.International journal of colorectal disease · 2021Pooled it
- Anorectal emergencies: WSES-AAST guidelines.World journal of emergency surgery : WJES · 2021Pooled it
- Management options for chronic anal fissure: a systematic review of randomised controlled trials.International journal of colorectal disease · 2020Pooled it
- Pelvic floor physical therapy in the treatment of chronic anal fissure (PAF trial): quality of life outcome.Techniques in coloproctology · 2023Trial
- Pelvic floor physical therapy in patients with chronic anal fissure: a randomized controlled trial.Techniques in coloproctology · 2022Trial
- Potential combination topical therapy of anal fissure: development, evaluation, and clinical study†.Drug delivery · 2018Trial
- Efficacy of an Ayurvedic Management Protocol on the Rate of Recurrence, Healing and Safety in Parikarthika (Fissure in Ano): Protocol for a Randomized Controlled Trial.JMIR research protocols · 2026Article
- Global Management of Anal Fissure: Results from the ISUCRS 2022 Snapshot Audit.Journal of clinical medicine · 2026Article
- Impact of sentinel pile on botulinum toxin treatment of chronic anal fissure: A comparative study.Techniques in coloproctology · 2026Observational
- Assessment of Treatment Effectiveness in Acute and Chronic Anal Fissures.Medicina (Kaunas, Lithuania) · 2026Article
- Therapy and long-term outcomes of acute anal fissure: a high-volume referral centre experience with 623 patients.Techniques in coloproctology · 2026Article
- [Chronic anal fissure-Cremes or surgery?]Chirurgie (Heidelberg, Germany) · 2025Review
- The Effect of Sphincter Pressure and Anal Length on Surgical Decision in Chronic Anal Fissure.Journal of clinical medicine · 2025Article
- Toilet behaviors and lifestyle factors in anorectal diseases: a cross-sectional analysis.Frontiers in surgery · 2025Article
- Chili pepper consumption and duration of fissure symptoms onset are associated with perianal fistula development among patients with anal fissure: a case-control study.BMC nutrition · 2024Article
- Anal fissures in COVID-19 survivors: Incidence, risk factors, and outcomes.Turkish journal of surgery · 2024Article
- Is chemodenervation with incobotulinumtoxinA an alternative to invasive chronic anal fissure treatments?BMC gastroenterology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anal fissure (fissure-in-ano) is a very common anorectal condition. The exact etiology of this condition is debated; however, there is a clear association with elevated internal anal sphincter pressures. Though hard bowel movements are implicated in fissure etiology, they are not universally present in patients with anal fissures. Half of all patients with fissures heal with nonoperative management such as high fiber diet, sitz baths, and pharmacological agents. When nonoperative management fails, surgical treatment with lateral internal sphincterotomy has a high success rate. In this chapter, we will review the symptoms, pathophysiology, and management of anal fissures.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.