Evidence map›Paper›PMID 26929654›Full record

ReviewClinicoEconomics and outcomes research : CEOR2016

Costs associated with rheumatoid arthritis in Italy: past, present, and future.

Maurizio Benucci, Veronica Rogai, Fabiola Atzeni, Volker Hammen, Piercarlo Sarzti-Puttini, Alberto Migliore

Open access · goldAbstract readReview
In one paragraph

Review in ClinicoEconomics and outcomes research : CEOR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Indirect Costs of Rheumatoid Arthritis Depending on Type of Treatment-A Systematic Literature Review.International journal of environmental research and public health · 2019
    Pooled it
  2. Management of Rheumatoid Arthritis in Primary Care: A Scoping Review.International journal of environmental research and public health · 2024
    Article
  3. Vitiligo: Epidemiology and Economic Impact.Dermatology practical & conceptual · 2023
    Review
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Maurizio BenucciRheumatology Unit, S.Giovanni di Dio Hospital, Florence, Italy.
Veronica RogaiEli Lilly Italia SpA, Sesto Fiorentino, Italy.
Fabiola AtzeniRheumatology Unit, L Sacco Hospital, Milan, Italy.
Volker HammenLilly Deutschland GmbH, Bad Homburg, Germany.
Piercarlo Sarzti-PuttiniRheumatology Unit, L Sacco Hospital, Milan, Italy.
Alberto MiglioreVilla San Pietro Fatebenefratelli Hospital, Rome, Italy.
Luigi Sacco Hospital · ITEli Lilly (Germany) · DEEli Lilly (Italy) · ITFatebenefratelli Hospital · ITNuovo Ospedale San Giovanni di Dio · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This literature review examines available evidence on the current and past costs associated with rheumatoid arthritis (RA) in Italy, together with the future health-economic prospects for the disease. Studies have been conducted to date on the prevalence, or the associated costs, of RA in Italy. Although future changes in the incidence of RA are a matter of debate, the impact of RA on health care costs is expected to grow in coming decades in line with projected increases in life expectancy and in the proportion of elderly people in Italy. It has been estimated that the indirect (productivity loss and informal care) and intangible (deterioration in health-related quality of life) costs of the disease will contribute to an increase in national health service expenditure, which will correspond to 1% of the total health care costs of the nation in the near future. The introduction of biological agents for the treatment of rheumatic diseases has resulted in an increase in the direct costs of RA; however, economic analyses that exclude indirect costs will underestimate the full economic impact of RA. The effectiveness of innovative therapies in preventing disease progression and functional impairment may, over time, attenuate the cost impact of RA in terms of hospitalizations and work absenteeism. Further research is needed to develop estimates of the economic impact of different therapeutic approaches in patients with RA in Italy, in order to provide tools that can drive the choice of the most cost-effective therapeutic option while maintaining high-quality care.

Indexed as

disease costsItalyprevalencerheumatoid arthritis

Identifiers

PMID26929654
PMCPMC4754095
OpenAlexW2252294144

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.