Evidence map›Paper›PMID 26929639›Full record

ReviewOncoTargets and therapy2016

Long noncoding RNAs in gastric cancer: functions and clinical applications.

Jiajun Wang, Jingxu Sun, Jun Wang, Yongxi Song, Peng Gao, Jinxin Shi, Ping Chen, Zhenning Wang

Open access · goldAbstract readReview
In one paragraph

Review in OncoTargets and therapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. FAM117A and PIGU regulate the trilogy of gastric carcinogenesis.Computational and structural biotechnology journal · 2025
    Article
  3. Article
  4. Gastric Cancer in the Era of Epigenetics.International journal of molecular sciences · 2024
    Review
  5. Review
  6. Article
  7. Review
  8. Gastric cancer: An epigenetic view.World journal of gastrointestinal oncology · 2022
    Review
  9. Article
  10. +HOXA10-AS Promotes Malignant Phenotypes of Gastric Cancer via Upregulating HOXA10.Computational and mathematical methods in medicine · 2022
    Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Recent advances in gastric cancer early diagnosis.World journal of gastroenterology · 2019
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jiajun WangDepartment of Surgical Oncology and General Surgery, First Hospital of China Medical University, Shenyang, People's Republic of China.
Jingxu SunDepartment of Surgical Oncology and General Surgery, First Hospital of China Medical University, Shenyang, People's Republic of China.
Jun WangDepartment of Surgical Oncology and General Surgery, First Hospital of China Medical University, Shenyang, People's Republic of China.
Yongxi SongDepartment of Surgical Oncology and General Surgery, First Hospital of China Medical University, Shenyang, People's Republic of China.
Peng GaoDepartment of Surgical Oncology and General Surgery, First Hospital of China Medical University, Shenyang, People's Republic of China.
Jinxin ShiDepartment of Surgical Oncology and General Surgery, First Hospital of China Medical University, Shenyang, People's Republic of China.
Ping ChenDepartment of Surgical Oncology and General Surgery, First Hospital of China Medical University, Shenyang, People's Republic of China.
Zhenning WangDepartment of Surgical Oncology and General Surgery, First Hospital of China Medical University, Shenyang, People's Republic of China.
First Hospital of China Medical University · CNChina Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the last two decades, genome-wide studies have revealed that only a small fraction of the human genome encodes proteins; long noncoding RNAs (lncRNAs) account for 98% of the total genome. These RNA molecules, which are >200 nt in length, play important roles in diverse biological processes, including the immune response, stem cell pluripotency, cell proliferation, apoptosis, differentiation, invasion, and metastasis by regulating gene expression at the epigenetic, transcriptional, and posttranscriptional levels. However, the detailed molecular mechanisms underlying lncRNA function are only partially understood. Recent studies showed that many lncRNAs are aberrantly expressed in gastric cancer (GC) tissues, gastric juice, plasma, and cells, and these alterations are linked to the occurrence, progression, and outcome of GC. Here, we review the current knowledge of the biological functions and clinical aspects of lncRNAs in GC.

Indexed as

biomarkergastric cancerlong noncoding RNAtarget therapy

Identifiers

PMID26929639
PMCPMC4755433
OpenAlexW2257625229

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.