Evidence map›Paper›PMID 26929062›Full record

Observational studyJournal of hospital medicine2016

Predicting all-cause readmissions using electronic health record data from the entire hospitalization: Model development and comparison.

Oanh Kieu Nguyen, Anil N Makam, Christopher Clark, Song Zhang, Bin Xie, Ferdinand Velasco, Ruben Amarasingham, Ethan A Halm

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of hospital medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 2 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 78 citations in OpenAlex.

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  14. Implementing an Individual-Centric Discharge Process across Singapore Public Hospitals.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Oanh Kieu NguyenDivision of General Internal Medicine, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, Texas.
Anil N MakamDivision of General Internal Medicine, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, Texas.
Christopher ClarkParkland Center for Clinical Innovation (PCCI), Dallas, Texas.
Song ZhangDivision of Biostatistics, Department of Clinical Sciences, UT Southwestern Medical Center, Dallas, Texas.
Bin XieParkland Center for Clinical Innovation (PCCI), Dallas, Texas.
Ferdinand VelascoTexas Health Resources, Dallas, Texas.
Ruben AmarasinghamDivision of General Internal Medicine, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, Texas.
Ethan A HalmDivision of General Internal Medicine, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, Texas.
Southwestern Medical CenterParkland Center For Clinical Innovation · USTexas Health Resources Foundation · USThe University of Texas Southwestern Medical Center · US

Funding

UT Southwestern Center for Translational Medicine (UL1/KL2/TL1)UL1TR001105 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2013 to 2017
$24.5M
UT Southwestern Center of Patient-Centered Outcomes Research (PCOR)R24HS022418 · AHRQ · UT SOUTHWESTERN MEDICAL CENTER · PI HALM, ETHAN A · 2013 to 2017
$5.0M
UT Southwestern Center for Translational Medicine (UL1/KL2/TL1KL2TR001103 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2013 to 2017
$4.0M
AHRQ HHS R24 HS022418NCATS NIH HHS KL2 TR001103NCATS NIH HHS UL1 TR001105
6 · The paper itself

Abstract

backgroundIncorporating clinical information from the full hospital course may improve prediction of 30-day readmissions.

objectiveTo develop an all-cause readmissions risk-prediction model incorporating electronic health record (EHR) data from the full hospital stay, and to compare "full-stay" model performance to a "first day" and 2 other validated models, LACE (includes Length of stay, Acute [nonelective] admission status, Charlson Comorbidity Index, and Emergency department visits in the past year), and HOSPITAL (includes Hemoglobin at discharge, discharge from Oncology service, Sodium level at discharge, Procedure during index hospitalization, Index hospitalization Type [nonelective], number of Admissions in the past year, and Length of stay).

designObservational cohort study. SUBJECTS: All medicine discharges between November 2009 and October 2010 from 6 hospitals in North Texas, including safety net, teaching, and nonteaching sites. MEASURES: Thirty-day nonelective readmissions were ascertained from 75 regional hospitals.

resultsAmong 32,922 admissions (validation = 16,430), 12.7% were readmitted. In addition to many first-day factors, we identified hospital-acquired Clostridium difficile infection (adjusted odds ratio [AOR]: 2.03, 95% confidence interval [CI]: 1.18-3.48), vital sign instability on discharge (AOR: 1.25, 95% CI: 1.15-1.36), hyponatremia on discharge (AOR: 1.34, 95% CI: 1.18-1.51), and length of stay (AOR: 1.06, 95% CI: 1.04-1.07) as significant predictors. The full-stay model had better discrimination than other models though the improvement was modest (C statistic 0.69 vs 0.64-0.67). It was also modestly better in identifying patients at highest risk for readmission (likelihood ratio +2.4 vs. 1.8-2.1) and in reclassifying individuals (net reclassification index 0.02-0.06).

conclusionsIncorporating clinically granular EHR data from the full hospital stay modestly improves prediction of 30-day readmissions. Given limited improvement in prediction despite incorporation of data on hospital complications, clinical instabilities, and trajectory, our findings suggest that many factors influencing readmissions remain unaccounted for. Further improvements in readmission models will likely require accounting for psychosocial and behavioral factors not currently captured by EHRs. Journal of Hospital Medicine 2016;11:473-480. © 2016 Society of Hospital Medicine.

Indexed as

Cohort StudiesElectronic Health RecordsEmergency Service, HospitalFemaleHospitalizationHumansLength of StayMaleMiddle AgedModels, TheoreticalPatient ReadmissionRisk FactorsTexas

Identifiers

PMID26929062
PMCPMC5365027
OpenAlexW2279842060

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.