ArticleScientific reports2016
Family conflict and lower morning cortisol in adolescents and adults: modulation of puberty.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Oral Lorazepam is not Superior to Placebo for Lowering Stress in Children Before Digestive Endoscopy: A Double-Blind, Randomized, Controlled Trial.Paediatric drugs · 2019Trial
- Does including multiple hormones and family context together clarify hormone-behavior associations? A systematic review.Comprehensive psychoneuroendocrinology · 2025Review
- Current Family Functioning and Youth Cardiometabolic Health in the SOL Youth Study.International journal of behavioral medicine · 2023Article
- Association between Psychopathological Symptoms and Aggression and Selected Biochemical Parameters in Adolescents with Behavioural and Emotional Disturbances.International journal of molecular sciences · 2023Article
- Chronic Stress in Children and Adolescents: A Review of Biomarkers for Use in Pediatric Research.Biological research for nursing · 2018Article
- Translational relevance of rodent models of hypothalamic-pituitary-adrenal function and stressors in adolescence.Neurobiology of stress · 2017Review
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We aimed to explore the association between family conflict and HPA axis activity, especially with respect to the potential modulating effect of puberty. A total of 205 adolescents and 244 adult parents were recruited. Family conflict was assessed by the family conflict subscale of the Family Environmental Scale and serial salivary cortisol was measured in all participants. A marginally lower AUCg at 30 minutes after wake up in the morning and a significant lower AUCg at 60 minutes and 90 minutes in adult parents with high family conflict was found when compared to those with low family conflict. In adolescents, there were significant interaction effects between pubertal status and family conflict on AUCg (interaction p values <0.05). Among the adolescents with low family conflict, those at late/post pubertal status had higher AUCg than their pre/early pubertal counterparts but this difference was not observed in the adolescents with high family conflict. Adverse family environment is associated with HPA axis dysfunction in adults and late/post pubertal adolescents and pubertal maturation plays a critical role in modulating the association between family environment and HPA axis function.
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Registered trials
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