Evidence map›Paper›PMID 26928807›Full record

ArticleHypertension (Dallas, Tex. : 1979)2016

Intrarenal Renin-Angiotensin System: Locally Synthesized or Taken up Via Endocytosis?

Richard J Roman, Fan Fan, Jia L Zhuo

Abstract readEditorialComment
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. The relationship between estrogen and renin angiotensin system components in the context of hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Review
  3. Article
  4. COVID's Razor: RAS Imbalance, the Common Denominator Across Disparate, Unexpected Aspects of COVID-19.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020
    Review
  5. Angiotensin III/ATJournal of the American Heart Association · 2019
    Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Richard J RomanFrom the Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson. rroman@umc.edu.
Fan FanFrom the Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson.
Jia L ZhuoFrom the Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson.

Funding

The role of leptin in autoimmune-associated hypertensionP20GM104357 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI TAYLOR, ERIN BASSFORD · 2013 to 2022
$23.4M
Role of Intracrine Angiotensin II in Kidney CellsR01DK067299 · NIDDK · UNIVERSITY OF MISSISSIPPI MED CTR · PI Jia Long Zhuo · 2004 to 2026
$6.5M
20-HETE-TGF-beta in Hypertension-Induced Renal InjuryR37HL036279 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI ROMAN, RICHARD J. · 2005 to 2014
$4.0M
Role of Proximal Tubule NHE3 in Angiotensin II-induced HypertensionR01DK102429 · NIDDK · UNIVERSITY OF MISSISSIPPI MED CTR · PI ZHUO, JIA LONG · 2014 to 2021
$2.5M
Renal microcirculation and hypertension induced renal injuryR01DK104184 · NIDDK · UNIVERSITY OF MISSISSIPPI MED CTR · PI ROMAN, RICHARD J. · 2014 to 2017
$1.8M
VASA RECTA HEMODYNAMICS IN GENETIC HYPERTENSIONR01HL036279 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI ROMAN, RICHARD J. · 1986 to 2004
$1.3M
Animal model of impaired autoregulation for study of age related vascular cognitive impairmentR21AG050049 · NIA · UNIVERSITY OF MISSISSIPPI MED CTR · PI FAN, FAN · 2016 to 2017
$419k
Novel Roles of Intracrine Angiotensin II in Proximal Tubule CellsR56DK067299 · NIDDK · HENRY FORD HEALTH SYSTEM · PI ZHUO, JIA LONG · 2009 to 2009
$352k
NHLBI NIH HHS HL36279NHLBI NIH HHS R01 HL036279NHLBI NIH HHS R37 HL036279NIA NIH HHS AG050049NIA NIH HHS R21 AG050049NIDDK NIH HHS DK067299NIDDK NIH HHS DK102429NIDDK NIH HHS DK104184NIDDK NIH HHS R01 DK067299NIDDK NIH HHS R01 DK102429NIDDK NIH HHS R01 DK104184NIDDK NIH HHS R56 DK067299NIGMS NIH HHS P20 GM104357NIGMS NIH HHS P20GM104357
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Renin-Angiotensin SystemAngiotensin IIAngiotensinogenEndocytosisHumansKidneyReninAngiotensin IIAngiotensinogenRenin

Identifiers

PMID26928807
PMCPMC4833086

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.