Evidence map›Paper›PMID 26928390›Full record

ArticleMolecular medicine (Cambridge, Mass.)2016

Increased Risk of Interstitial Lung Disease in Children with a Single R288K Variant of ABCA3.

Thomas Wittmann, Sabrina Frixel, Stefanie Höppner, Ulrike Schindlbeck, Andrea Schams, Matthias Kappler, Jan Hegermann, Christoph Wrede, Gerhard Liebisch, Anne Vierzig and 10 more

Open access · goldAbstract read
In one paragraph

Article in Molecular medicine (Cambridge, Mass.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Systematic review of drug effects in humans and models with surfactant-processing disease.European respiratory review : an official journal of the European Respiratory Society · 2018
    Pooled it
  2. Review
  3. Article
  4. Genetic Strategies for Labeling AT2 Cells in Murine Lung via Abca3 and Etv5-Driven Reporters.Journal of respiratory biology and translational medicine · 2026
    Article
  5. Review
  6. Biomedicines · 2024
    Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Quantifying Functional Impairment ofInternational journal of molecular sciences · 2023
    Article
  12. Article
  13. Article
  14. Structure-Based Understanding of ABCA3 Variants.International journal of molecular sciences · 2021
    Article
  15. Translational pediatrics · 2021
    Article
  16. A NewMedicina (Kaunas, Lithuania) · 2019
    Article
  17. Genetic causes of surfactant protein abnormalities.Current opinion in pediatrics · 2019
    Review
  18. Article
  19. Chronic interstitial lung disease in children.European respiratory review : an official journal of the European Respiratory Society · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 8 institutions in 3 countries.

Thomas WittmannDr. von Hauner Children's Hospital, Ludwig-Maximilians University, German Lung Research Center (DZL), Munich, Germany.
Sabrina FrixelDr. von Hauner Children's Hospital, Ludwig-Maximilians University, German Lung Research Center (DZL), Munich, Germany.
Stefanie HöppnerDr. von Hauner Children's Hospital, Ludwig-Maximilians University, German Lung Research Center (DZL), Munich, Germany.
Ulrike SchindlbeckDr. von Hauner Children's Hospital, Ludwig-Maximilians University, German Lung Research Center (DZL), Munich, Germany.
Andrea SchamsDr. von Hauner Children's Hospital, Ludwig-Maximilians University, German Lung Research Center (DZL), Munich, Germany.
Matthias KapplerDr. von Hauner Children's Hospital, Ludwig-Maximilians University, German Lung Research Center (DZL), Munich, Germany.
Jan HegermannInstitute of Functional and Applied Anatomy, Hannover Medical School, German Lung Research Center (DZL), Hannover, Germany.
Christoph WredeInstitute of Functional and Applied Anatomy, Hannover Medical School, German Lung Research Center (DZL), Hannover, Germany.
Gerhard LiebischInstitute for Clinical Chemistry and Laboratory Medicine, University of Regensburg, Regensburg, Germany.
Anne VierzigPaediatric Intensive Care, University Children's Hospital, University of Cologne, Cologne, Germany.
Angela ZacharasiewiczDepartment of Pediatrics, Wilhelminenspital, Vienna, Austria.
Matthias Volkmar KoppDepartment of Pediatric Allergy and Pulmonology, University Löbeck, Airway Research Center North (ARCN), Löbeck, Germany.
Christian F PoetsChildren's Hospital, University of Töbingen, Töbingen, Germany.
Winfried BadenChildren's Hospital, University of Töbingen, Töbingen, Germany.
Dominik HartlChildren's Hospital, University of Töbingen, Töbingen, Germany.
Anton H van KaamDepartment of Neonatology, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.
Peter LohseHohentwielstr. 32, Tengen, Germany.
Charalampos AslanidisInstitute for Clinical Chemistry and Laboratory Medicine, University of Regensburg, Regensburg, Germany.
Ralf ZarbockDr. von Hauner Children's Hospital, Ludwig-Maximilians University, German Lung Research Center (DZL), Munich, Germany.
Matthias GrieseDr. von Hauner Children's Hospital, Ludwig-Maximilians University, German Lung Research Center (DZL), Munich, Germany.
Ludwig-Maximilians-Universität München · DEMedizinische Hochschule Hannover · DEUniversity Children's Hospital Tübingen · DEUniversity of Regensburg · DEAcademic Medical Center · NLUniversity Hospital Cologne · DEUniversity of Tübingen · DEWilhelminen Hospital · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The

Identifiers

PMID26928390
PMCPMC5004714
OpenAlexW2289437492

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.