ArticleBMJ open2016
Evaluating the impacts of screening and smoking cessation programmes on lung cancer in a high-burden region of the USA: a simulation modelling study.
Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Identifying best modelling practices for tobacco control policy simulations: a systematic review and a novel quality assessment framework.Tobacco control · 2023Pooled it
- Interventions for smoking cessation in people undergoing lung cancer screening.The Cochrane database of systematic reviews · 2026Article
- Natural history models for lung Cancer: A scoping review.Lung cancer (Amsterdam, Netherlands) · 2025Article
- Motivation, acceptability and attitudes toward lung cancer screening among persons who attend a tobacco cessation program: A multicenter survey in Italy.Preventive medicine reports · 2023Article
- "It's a decision I have to make": Patient perspectives on smoking and cessation after lung cancer screening decisions.Preventive medicine reports · 2022Article
- Article
- Implementation of lung cancer screening: what are the main issues?Translational lung cancer research · 2021Review
- Lung cancer screening and smoking cessation efforts.Translational lung cancer research · 2021Review
- Building a tobacco user registry by extracting multiple smoking behaviors from clinical notes.BMC medical informatics and decision making · 2019Article
- A simulation study of the effect of lung cancer screening in China, Japan, Singapore, and South Korea.PloS one · 2019Article
- How can we better help cancer patients quit smoking? The London Regional Cancer Program experience with smoking cessation.Current oncology (Toronto, Ont.) · 2018Review
- Population impact of lung cancer screening in the United States: Projections from a microsimulation model.PLoS medicine · 2018Article
- Challenges of quitting smoking and lung cancer screening.Annals of translational medicine · 2017Article
- Lung Cancer Screening.The Medical clinics of North America · 2017Review
- Tumor-node-metastasis staging and treatment patterns of 73,167 patients with lung cancer in Brazil.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e TisilogiaArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
objectiveWhile the US Preventive Services Task Force has issued recommendations for lung cancer screening, its effectiveness at reducing lung cancer burden may vary at local levels due to regional variations in smoking behaviour. Our objective was to use an existing model to determine the impacts of lung cancer screening alone or in addition to increased smoking cessation in a US region with a relatively high smoking prevalence and lung cancer incidence.
settingComputer-based simulation model.
participantsSimulated population of individuals 55 and older based on smoking prevalence and census data from Northeast Pennsylvania.
interventionsHypothetical lung cancer control from 2014 to 2050 through (1) screening with CT, (2) intensified smoking cessation or (3) a combination strategy. PRIMARY AND SECONDARY OUTCOME MEASURES: Primary outcomes were lung cancer mortality rates. Secondary outcomes included number of people eligible for screening and number of radiation-induced lung cancers.
resultsCombining lung cancer screening with increased smoking cessation would yield an estimated 8.1% reduction in cumulative lung cancer mortality by 2050. Our model estimated that the number of screening-eligible individuals would progressively decrease over time, indicating declining benefit of a screening-only programme. Lung cancer screening achieved a greater mortality reduction in earlier years, but was later surpassed by smoking cessation.
conclusionsCombining smoking cessation programmes with lung cancer screening would provide the most benefit to a population, especially considering the growing proportion of patients ineligible for screening based on current recommendations.
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