ArticlePLoS biology2016
Social Evolution Selects for Redundancy in Bacterial Quorum Sensing.
Article in PLoS biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 73 citations in OpenAlex.
- ArcB initiates quorum sensing to regulate T3SS in Vibrio alginolyticus by recognizing bacterial and host-derived autoinducer-2 as a kinase.Cell communication and signaling : CCS · 2025Article
- Constructions of quorum sensing signaling network for activated sludge microbial community.ISME communications · 2024Article
- Crosstalk enables mutual activation of coupled quorum sensing pathways through "jump-start" and "push-start" mechanisms.Scientific reports · 2023Article
- Large-Scale Identification of Known and Novel RRNPP Quorum-Sensing Systems by RRNPP_Detector Captures Novel Features of Bacterial, Plasmidic, and Viral Coevolution.Molecular biology and evolution · 2023Article
- Complex extracellular biology drives surface competition during colony expansion in Bacillus subtilis.The ISME journal · 2022Article
- Article
- Mechanisms of interactions between bacteria and bacteriophage mediate by quorum sensing systems.Applied microbiology and biotechnology · 2022Review
- Public communication can facilitate low-risk coordination under surveillance.Scientific reports · 2022Article
- Impact of Rap-Phr system abundance on adaptation of Bacillus subtilis.Communications biology · 2021Article
- Ten recent insights for our understanding of cooperation.Nature ecology & evolution · 2021Review
- Article
- A Bacterial Tower of Babel: Quorum-Sensing Signaling Diversity and Its Evolution.Annual review of microbiology · 2020Review
- Rap-Phr Systems from Plasmids pAW63 and pHT8-1 Act Together To Regulate Sporulation in the Bacillus thuringiensis Serovar kurstaki HD73 Strain.Applied and environmental microbiology · 2020Article
- Article
- RRNPP-type quorum sensing affects solvent formation and sporulation inMicrobiology (Reading, England) · 2020Article
- In silico bacteria evolve robust cooperaion via complex quorum-sensing strategies.Scientific reports · 2020Article
- Multiple and Overlapping Functions of Quorum Sensing Proteins for Cell Specialization inJournal of bacteriology · 2020Review
- Fitness and Productivity Increase with Ecotypic Diversity amongApplied and environmental microbiology · 2020Article
- The complete genome sequence of the algicidal bacteriumBiotechnology reports (Amsterdam, Netherlands) · 2020Article
- Rap Protein Paralogs of Bacillus thuringiensis: a Multifunctional and Redundant Regulatory Repertoire for the Control of Collective Functions.Journal of bacteriology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
Quorum sensing is a process of chemical communication that bacteria use to monitor cell density and coordinate cooperative behaviors. Quorum sensing relies on extracellular signal molecules and cognate receptor pairs. While a single quorum-sensing system is sufficient to probe cell density, bacteria frequently use multiple quorum-sensing systems to regulate the same cooperative behaviors. The potential benefits of these redundant network structures are not clear. Here, we combine modeling and experimental analyses of the Bacillus subtilis and Vibrio harveyi quorum-sensing networks to show that accumulation of multiple quorum-sensing systems may be driven by a facultative cheating mechanism. We demonstrate that a strain that has acquired an additional quorum-sensing system can exploit its ancestor that possesses one fewer system, but nonetheless, resume full cooperation with its kin when it is fixed in the population. We identify the molecular network design criteria required for this advantage. Our results suggest that increased complexity in bacterial social signaling circuits can evolve without providing an adaptive advantage in a clonal population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.