ArticleJournal of biomedical optics2016
Optical oximetry of volume-oscillating vascular compartments: contributions from oscillatory blood flow.
Article in Journal of biomedical optics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- Melanin- and linewidth-corrected pulse-oximetry.ArXiv · 2026Article
- Assessment of cerebral autoregulation and cerebral perfusion in patients with sickle cell disease using frequency-domain near-infrared spectroscopy.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Article
- Plasma Volume Oscillations During Intravenous Infusion of Hyper-Oncotic Albumin.Life (Basel, Switzerland) · 2025Article
- Critical analysis of the relationship between arterial saturation and the ratio-of-ratios used in pulse oximetry.Journal of biomedical optics · 2024Article
- Dual-ratio approach to pulse oximetry and the effect of skin tone.Journal of biomedical optics · 2024Article
- High optode-density wearable diffuse optical probe for monitoring paced breathing hemodynamics in breast tissue.Journal of biomedical optics · 2021Article
- Dynamic cerebral autoregulation estimates derived from near infrared spectroscopy and transcranial Doppler are similar after correction for transit time and blood flow and blood volume oscillations.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020Article
- Depth dependence of coherent hemodynamics in the human head.Journal of biomedical optics · 2018Article
- Assessing low-frequency oscillations in cerebrovascular diseases and related conditions with near-infrared spectroscopy: a plausible method for evaluating cerebral autoregulation?Neurophotonics · 2018Review
- Correlation between Cerebral Hemodynamic and Perfusion Pressure Changes in Non-Human Primates.Proceedings of SPIE--the International Society for Optical Engineering · 2017Article
- Blood-pressure-induced oscillations of deoxy- and oxyhemoglobin concentrations are in-phase in the healthy breast and out-of-phase in the healthy brain.Journal of biomedical optics · 2016Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
We present a quantitative analysis of dynamic diffuse optical measurements to obtain oxygen saturation of hemoglobin in volume oscillating compartments. We used a phasor representation of oscillatory hemodynamics at the heart rate and respiration frequency to separate the oscillations of tissue concentrations of oxyhemoglobin (O) and deoxyhemoglobin (D) into components due to blood volume (subscript V V ) and blood flow (subscript F F ): O=O V +O F O=OV+OF , D=D V +D F D=DV+DF . This is achieved by setting the phase angle Arg(O F )−Arg(O) Arg(OF)−Arg(O) , which can be estimated by a hemodynamic model that we recently developed. We found this angle to be −72 deg −72 deg for the cardiac pulsation at 1 Hz, and −7 deg −7 deg for paced breathing at 0.1 Hz. Setting this angle, we can obtain the oxygen saturation of hemoglobin of the volume-oscillating vascular compartment, S V =|O V |/(|O V |+|D V |) SV=|OV|/(|OV|+|DV|) . We demonstrate this approach with cerebral near-infrared spectroscopy measurements on healthy volunteers at rest (n=4 n=4 ) and during 0.1 Hz paced breathing (n=3 n=3 ) with a 24-channel system. Rest data at the cardiac frequency were used to calculate the arterial saturation, S (a) S(a) ; over all subjects and channels, we found ⟨S V ⟩=⟨S (a) ⟩=0.96±0.02 ⟨SV⟩=⟨S(a)⟩=0.96±0.02 . In the case of paced breathing, we found ⟨S V ⟩=0.66±0.14 ⟨SV⟩=0.66±0.14 , which reflects venous-dominated hemodynamics at the respiratory frequency.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.