Evidence map›Paper›PMID 26926695›Full record

ReviewAnnals of biomedical engineering2016

Artificial Muscle Devices: Innovations and Prospects for Fecal Incontinence Treatment.

Elisa Fattorini, Tobia Brusa, Christian Gingert, Simone E Hieber, Vanessa Leung, Bekim Osmani, Marco D Dominietto, Philippe Büchler, Franc Hetzer, Bert Müller

Abstract readReview
In one paragraph

Review in Annals of biomedical engineering, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Bio-inspired circular soft actuators for simulating defecation process of human rectum.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2025
    Article
  3. Review
  4. Problems with repairing gut sphincters malfunctions.World journal of gastrointestinal surgery · 2024
    Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Elisa FattoriniDepartment of Surgery and Orthopedics, Hospitals Schaffhausen, 8200, Schaffhausen, Switzerland.
Tobia BrusaInstitute for Surgical Technology & Biomechanics, University of Bern, 3014, Bern, Switzerland.
Christian GingertDepartment of Surgery and Orthopedics, Hospitals Schaffhausen, 8200, Schaffhausen, Switzerland.
Simone E HieberBiomaterials Science Center, University of Basel, 4123, Allschwil, Switzerland.
Vanessa LeungBiomaterials Science Center, University of Basel, 4123, Allschwil, Switzerland.
Bekim OsmaniBiomaterials Science Center, University of Basel, 4123, Allschwil, Switzerland.
Marco D DominiettoDepartment of Surgery and Orthopedics, Hospitals Schaffhausen, 8200, Schaffhausen, Switzerland.
Philippe BüchlerInstitute for Surgical Technology & Biomechanics, University of Bern, 3014, Bern, Switzerland.
Franc HetzerDepartment of Surgery and Orthopedics, Hospitals Schaffhausen, 8200, Schaffhausen, Switzerland.
Bert MüllerBiomaterials Science Center, University of Basel, 4123, Allschwil, Switzerland. bert.mueller@unibas.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fecal incontinence describes the involuntary loss of bowel content, which is responsible for stigmatization and social exclusion. It affects about 45% of retirement home residents and overall more than 12% of the adult population. Severe fecal incontinence can be treated by the implantation of an artificial sphincter. Currently available implants, however, are not part of everyday surgery due to long-term re-operation rates of 95% and definitive explantation rates of 40%. Such figures suggest that the implants fail to reproduce the capabilities of the natural sphincter. This article reviews the artificial sphincters on the market and under development, presents their physical principles of operation and critically analyzes their performance. We highlight the geometrical and mechanical parameters crucial for the design of an artificial fecal sphincter and propose more advanced mechanisms of action for a biomimetic device with sensory feedback. Dielectric electro-active polymer actuators are especially attractive because of their versatility, response time, reaction forces, and energy consumption. The availability of such technology will enable fast pressure adaption comparable to the natural feedback mechanism, so that tissue atrophy and erosion can be avoided while maintaining continence during daily activities.

Indexed as

Anal CanalBiomimetic MaterialsFecal IncontinenceProsthesis DesignAdultArtificial OrgansHumansProsthesis FailureBiomimetic designElectro-active polymer actuatorFecal sphincter

Identifiers

PMID26926695
PMCPMC4837210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.