ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2016
Association of Financial Strain With Symptom Burden and Quality of Life for Patients With Lung or Colorectal Cancer.
Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 207 papers, 9 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
207 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Prevalence and determinants of financial toxicity in patients with colorectal cancer: a systematic review and meta-analysis.International journal for equity in health · 2026Pooled it
- Towards the assessment of financial distress among cancer patients: a conceptual model of the financial effects of a tumour disease.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Pooled it
- Counting the social, psychological, and economic costs of COVID-19 for cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Pooled it
- Patient Perceived Financial Burden in Haematological Malignancies: A Systematic Review.Current oncology (Toronto, Ont.) · 2022Pooled it
- Cost-effectiveness of physical activity interventions in cancer survivors of developed countries: a systematic review.Journal of cancer survivorship : research and practice · 2021Pooled it
- Health-related quality of life in patients with colorectal cancer in the palliative phase: a systematic review and meta-analysis.BMC palliative care · 2021Pooled it
- Financial Burdens of Cancer Treatment: A Systematic Review of Risk Factors and Outcomes.Journal of the National Comprehensive Cancer Network : JNCCN · 2019Pooled it
- Clinical decision support for therapeutic decision-making in cancer: A systematic review.International journal of medical informatics · 2019Pooled it
- Methods for measuring financial toxicity after cancer diagnosis and treatment: a systematic review and its implications.Annals of oncology : official journal of the European Society for Medical Oncology · 2019Pooled it
- Financial Navigation for People Newly Diagnosed With Cancer: Primary Outcomes From the Cancer Financial Experience Randomized Trial.JCO oncology practice · 2025Trial
- Factors Influencing Symptom Severity at Discharge after Lobectomy and Sublobar Resection Through Video-assisted Thoracoscopic Surgery.Interdisciplinary cardiovascular and thoracic surgery · 2025Trial
- Not all cost conversations are the same: An exploration of potential value in cost conversations during Atrial fibrillation treatment decision making.Patient education and counseling · 2024Trial
- Financial hardship experience in middle- and older-aged patients with advanced lung cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Trial
- A proactive financial navigation intervention in patients with newly diagnosed gastric and gastroesophageal junction adenocarcinoma.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Trial
- Financial Toxicity Monitoring in a Randomized Controlled Trial of Patient-Reported Outcomes During Cancer Treatment (Alliance AFT-39).Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023Trial
- Trial
- Professional patient navigation in a hospital setting: a randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Trial
- Prevalence, Risk Factors, and Outcomes of Financial Stress in Survivors of Critical Illness.Critical care medicine · 2018Trial
- Household material hardship in families of children post-chemotherapy.Pediatric blood & cancer · 2018Trial
- Assessing financial toxicity with COST-FACIT: experience from a tertiary care cancer center.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
147 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors.
Funding
Abstract
purposeTo measure the association between patient financial strain and symptom burden and quality of life (QOL) for patients with new diagnoses of lung or colorectal cancer. PATIENTS AND
methodsPatients participating in the Cancer Care Outcomes Research and Surveillance study were interviewed about their financial reserves, QOL, and symptom burden at 4 months of diagnosis and, for survivors, at 12 months of diagnosis. We assessed the association of patient-reported financial reserves with patient-reported outcomes including the Brief Pain Inventory, symptom burden on the basis of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire C30, and QOL on the basis of the EuroQoL-5 Dimension scale. Multivariable linear regression models were fit for each outcome and cancer type, adjusting for age, race/ethnicity, sex, income, insurance, stage at diagnosis, and comorbidity.
resultsAmong patients with lung and colorectal cancer, 40% and 33%, respectively, reported limited financial reserves (≤ 2 months). Relative to patients with more than 12 months of financial reserves, those with limited financial reserves reported significantly increased pain (adjusted mean difference, 5.03 [95% CI, 3.29 to 7.22] and 3.45 [95% CI, 1.25 to 5.66], respectively, for lung and colorectal), greater symptom burden (5.25 [95% CI, 3.29 to .22] and 5.31 [95% CI, 3.58 to 7.04]), and poorer QOL (4.70 [95% CI, 2.82 to 6.58] and 5.22 [95% CI, 3.61 to 6.82]). With decreasing financial reserves, a clear dose-response relationship was present across all measures of well-being. These associations were also manifest for survivors reporting outcomes again at 1 year and persisted after adjustment for stage, comorbidity, insurance, and other clinical attributes.
conclusionPatients with cancer and limited financial reserves are more likely to have higher symptom burden and decreased QOL. Assessment of financial reserves may help identify patients who need intensive support.
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