Evidence map›Paper›PMID 26926443›Full record

ArticleJournal of the American Society for Mass Spectrometry2016

Factors Affecting the Production of Aromatic Immonium Ions in MALDI 157 nm Photodissociation Studies.

Nick DeGraan-Weber, Daniel C Ashley, Karlijn Keijzer, Mu-Hyun Baik, James P Reilly

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In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nick DeGraan-WeberDepartment of Chemistry, Indiana University, 800 East Kirkwood Ave., Bloomington, IN, 47405, USA.
Daniel C AshleyDepartment of Chemistry, Indiana University, 800 East Kirkwood Ave., Bloomington, IN, 47405, USA.
Karlijn KeijzerDepartment of Chemistry, Indiana University, 800 East Kirkwood Ave., Bloomington, IN, 47405, USA.
Mu-Hyun BaikDepartment of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 339-701, South Korea. mbaik2805@kaist.ac.kr.
James P ReillyDepartment of Chemistry, Indiana University, 800 East Kirkwood Ave., Bloomington, IN, 47405, USA. reilly@indiana.edu.

Funding

Computational approaches to protein identification and quantification using MS/MSR01GM103725 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI RADIVOJAC, PREDRAG · 2012 to 2015
$1.7M
NIGMS NIH HHS R01 GM103725
6 · The paper itself

Abstract

Immonium ions are commonly observed in the high energy fragmentation of peptide ions. In a MALDI-TOF/TOF mass spectrometer, singly charged peptides photofragmented with 157 nm VUV light yield a copious abundance of immonium ions, especially those from aromatic residues. However, their intensities may vary from one peptide to another. In this work, the effect of varying amino acid position, peptide length, and peptide composition on immonium ion yield is investigated. Internal immonium ions are found to have the strongest intensity, whereas immonium ions arising from C-terminal residues are the weakest. Peptide length and competition among residues also strongly influence the immonium ion production. Quantum calculations provide insights about immonium ion structures and the fragment ion conformations that promote or inhibit immonium ion formation.

Indexed as

Amino Acids, AromaticArgininePeptidesPhotolysisSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationTandem Mass SpectrometryAmino Acids, AromaticArgininePeptidesAromatic residuesImmonium ionsPeptide ion fragmentationPhotodissociation

Identifiers

PMID26926443

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.