ArticleFertility and sterility2016
Maternal whole grain intake and outcomes of in vitro fertilization.
Article in Fertility and sterility, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00011713 (Human Exposure to Bisphenol A, Phthalates and Fertility, Pregnancy Outcomes.), which is not on this map. Cited by 29 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Human Exposure to Bisphenol A, Phthalates and Fertility, Pregnancy Outcomes.
Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Can Dietary Patterns Impact Fertility Outcomes? A Systematic Review and Meta-Analysis.Nutrients · 2023Pooled it
- Pooled it
- The Effect of Dietary Patterns on Clinical Pregnancy and Live Birth Outcomes in Men and Women Receiving Assisted Reproductive Technologies: A Systematic Review and Meta-Analysis.Advances in nutrition (Bethesda, Md.) · 2022Pooled it
- Preconception dietary patterns in association with live birth and pregnancy loss: a couples-based approach.Fertility and sterility · 2026Article
- Embryonic Mediators of Embryo-Uterus Communication, Implantation and Pregnancy.Molecular reproduction and development · 2026Review
- Article
- Metabolic Mechanisms Underlying the Association Between the Profertility Diet and In Vitro Fertilization End Points.The Journal of nutrition · 2025Article
- Multivitamin Supplementation and Fertility Outcome: A Retrospective Single-Center Cohort Study and the Clinical and Medicolegal Value of Nutritional Counseling.Life (Basel, Switzerland) · 2025Article
- Preconception diet quality and modified natural cycle in vitro fertilisation outcomes.Journal of nutritional science · 2025Article
- Examining the Role of Nutrition in Cancer Survivorship and Female Fertility: A Narrative Review.Current developments in nutrition · 2024Review
- Dietary Patterns and Fertility.Biology · 2024Review
- Assessing the influence of preconception diet on female fertility: a systematic scoping review of observational studies.Human reproduction update · 2023Article
- Women's Adherence to Healthy Dietary Patterns and Outcomes of Infertility Treatment.JAMA network open · 2023Article
- Development of a nutrition screening tool to identify need for dietetic intervention in female infertility.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2023Review
- Adherence to Nordic dietary patterns and risk of first-trimester spontaneous abortion.European journal of nutrition · 2022Article
- Female infertility and diet, is there a role for a personalized nutritional approach in assisted reproductive technologies? A Narrative Review.Frontiers in nutrition · 2022Review
- Review
- Can Nutrition Help in the Treatment of Infertility?Preventive nutrition and food science · 2021Review
- Review
- Nutrition in Gynecological Diseases: Current Perspectives.Nutrients · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
objectiveTo evaluate the relationship between pretreatment intake of whole grains and outcomes of IVF.
designProspective cohort study.
settingAcademic medical center. PATIENT(S): A total of 273 women who collectively underwent 438 IVF cycles. INTERVENTION(S): Whole grain intake was assessed with a validated food frequency questionnaire at enrollment. MAIN OUTCOME MEASURE(S): Intermediate and clinical end points of IVF were abstracted from medical records. RESULT(S): Women had a median whole grain intake of 34.2 g per day (∼1.2 servings/day). Higher pretreatment whole grain intake was associated with higher probability of implantation and live birth. The adjusted percentage of cycles resulting in live birth for women in the highest quartile of whole grain intake (>52.4 g/day) was 53% (95% confidence interval [CI] 41%, 65%) compared with 35% (95% CI 25%, 46%) for women in the lowest quartile (<21.4 g/day). This association was largely driven by intake of bran as opposed to germ. When intermediate end points of IVF were examined, only endometrial thickness on the day of ET was associated with whole grain intake. A 28-g per day (∼1 serving/day) increase in whole grain intake was associated with a 0.4-mm (95% CI 0.1, 0.7 mm) increase in endometrial thickness. CONCLUSION(S): Higher pretreatment whole grain intake was related to higher probability of live birth among women undergoing IVF. The higher probability of live birth may result from increased endometrial thickness on the day of ET and improved embryo receptivity manifested in a higher probability of implantation.
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Registered trials
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