ArticleBone marrow transplantation2016
Relationship between neurocognitive functioning and medication management ability over the first 6 months following allogeneic stem cell transplantation.
Article in Bone marrow transplantation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Impact of Cognitive Rehabilitation on Cognitive and Functional Outcomes in Adult Cancer Survivors: A Systematic Review.Seminars in oncology nursing · 2024Pooled it
- The relationship between diet and cognitive function in adult cancer survivors: a systematic review.Journal of cancer survivorship : research and practice · 2019Pooled it
- Psychostimulants for cancer-related cognitive impairment in adult cancer survivors: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Pooled it
- Feasibility and Preliminary Effects of Acupuncture for Cognitive Dysfunction in Diverse Cancer Survivors: A Pilot, Randomized, Placebo-Controlled Trial.Current oncology (Toronto, Ont.) · 2025Trial
- Pattern of change and predictors of cognitive function in older adults receiving allogeneic hematopoietic cell transplantation using the Montreal cognitive assessment.Journal of cancer survivorship : research and practice · 2026Observational
- Adherence to pharmacological treatment after hematopoietic stem cell transplantation: context analysis.Revista brasileira de enfermagem · 2025Article
- Neuropsychological Evaluation for Oncology.Neurologic clinics · 2024Review
- Perspective on oral medication adherence among patients with acute graft-versus-host disease: a qualitative descriptive study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Cognitive performance and mortality among patients receiving autologous hematopoietic stem cell transplant.Journal of psychosocial oncology · 2024Article
- Patient-reported cognitive function among hematopoietic stem cell transplant and cellular therapy patients: a scoping review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Change in Neurocognitive Performance Among Patients with Non-Hodgkin Lymphoma in the First Year after Chimeric Antigen Receptor T Cell Therapy.Transplantation and cellular therapy · 2022Article
- The relationship between cognitive function and performance in instrumental activities of daily living in older adults.The British journal of occupational therapy · 2022Article
- The effect of mind-body exercise on cognitive function in cancer survivors: A systematic review.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2022Article
- Cognitive impairment in candidates for allogeneic hematopoietic stem cell transplantation.Bone marrow transplantation · 2022Article
- Article
- Rehabilitation after Allogeneic Haematopoietic Stem Cell Transplantation: A Special Challenge.Cancers · 2021Review
- Cancer-related cognitive impairment in patients with non-central nervous system malignancies: an overview for oncology providers from the MASCC Neurological Complications Study Group.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Review
- Pre-transplant Dementia is Associated with Poor Survival After Hematopoietic Stem Cell Transplantation: A Nationwide Cohort Study with Propensity Score Matched Control.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2021Article
- Late cognitive outcomes among allogeneic stem cell transplant survivors: follow-up data from a 6-year longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- Computerized cognitive training in post-treatment hematological cancer survivors: a feasibility study.Pilot and feasibility studies · 2021Article
Corrections and comments
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Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although neurocognitive impairment has been established as a major issue among cancer survivors, the real-world consequences of this impairment are unclear. This study investigated the relationship between neurocognitive functioning and medication management ability over time among 58 patients treated with allogeneic hematopoietic stem cell transplantation (HCT). Participants completed a neuropsychological test battery and a simulated medication management task at three time points: pre-transplant (T0), Day 100 (T1) and 6 months post transplant (T2). Neurocognitively impaired participants performed worse on the medication management task than neurocognitively normal participants at each time point, and were more likely to score in the impaired range of medication management ability post transplant (72% vs 20%, P<0.001 at T1; 67% vs 23%, P=0.013 at T2). In multivariate analyses, worse performance in executive functioning/working memory consistently predicted impaired medication management ability, even when controlling for sociodemographic and clinical confounders (odds ratio=0.89, 95% confidence interval (0.80, 0.98), P=0.023). Lower physical symptom distress also predicted impaired medication management ability, but this effect decreased over time. Self-reported cognitive problems were not correlated with medication management ability at any time point. Findings suggest that poor neurocognitive functioning, particularly in the domain of executive functioning/working memory, is associated with worse medication management ability within the first 6 months after allogeneic HCT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.