ArticleEpidemiology and infection2016
Diabetes mellitus and extrapulmonary tuberculosis: site distribution and risk of mortality.
Article in Epidemiology and infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Epidemiology of extrapulmonary tuberculosis, Alameda County, California, 2010-2021.Journal of clinical tuberculosis and other mycobacterial diseases · 2026Article
- Evaluating the Gaps in the Diagnosis and Treatment in Extra-Pulmonary Tuberculosis Patients Under National Tuberculosis Elimination Programme (NTEP) Guidelines: A Multicentric Cohort Study.Tropical medicine and infectious disease · 2025Article
- Distinct Clinical Features of Extrapulmonary and Disseminated Tuberculosis in HIV- and Non-HIV-Associated Immunosuppression: A Retrospective Cohort Study.Open forum infectious diseases · 2025Article
- Incidence and determinants of extrapulmonary tuberculosis in Egypt: a retrospective cohort study.Scientific reports · 2025Article
- Glutathione Depletion Exacerbates HepaticBiology · 2025Article
- Risk Factors for Extrapulmonary Tuberculosis Among US Veterans, 1990-2022.Open forum infectious diseases · 2024Article
- The American Association of Tissue Banks tissue donor screening for Mycobacterium tuberculosis-Recommended criteria and literature review.Transplant infectious disease : an official journal of the Transplantation Society · 2024Review
- Hematological Parameters as Potential Markers for Distinguishing Pulmonary Tuberculosis from Genitourinary Tuberculosis.Pathogens (Basel, Switzerland) · 2023Article
- Diabetes and bacterial co-infection are two independent risk factors for respiratory syncytial virus disease severity.Frontiers in medicine · 2023Article
- Association of Underlying Comorbidities and Sites of tuberculosis: an analysis using surveillance data.BMC pulmonary medicine · 2022Article
- Prevalence of type 2 diabetes and pre-diabetes among pulmonary and extrapulmonary tuberculosis patients of Bangladesh: A cross-sectional study.Endocrinology, diabetes & metabolism · 2022Article
- Pre-Diabetes Increases Tuberculosis Disease Severity, While High Body Fat Without Impaired Glucose Tolerance Is Protective.Frontiers in cellular and infection microbiology · 2021Article
- Treatment outcomes and risk factors of extra-pulmonary tuberculosis in patients with co-morbidities.BMC infectious diseases · 2019Article
- Negative tuberculin skin test result predicts all-cause mortality among tuberculosis patients with HIV and diabetes comorbidity.Annals of epidemiology · 2019Article
- Epidemiology of Extrapulmonary Tuberculosis among Inpatients, China, 2008-2017.Emerging infectious diseases · 2019Article
- Risk factors for extrapulmonary dissemination of tuberculosis and associated mortality during treatment for extrapulmonary tuberculosis.Emerging microbes & infections · 2018Article
- Prevalence of diabetes mellitus amongst hospitalized tuberculosis patients at an Indian tertiary care center: A descriptive analysis.PloS one · 2018Article
- Factors associated with extrapulmonary tuberculosis in comparison to pulmonary tuberculosis in patients with and without HIV in Bogotá, Colombia: an observational study.Therapeutic advances in infectious diseaseArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Scarce data exist on the relationship between diabetes and extrapulmonary tuberculosis (EPTB). We evaluated whether diabetes impacts site of TB and risk of death in patients with EPTB. We evaluated a cohort of TB cases from the state of Georgia between 2009 and 2012. Patients aged ⩾16 years were classified by diabetes status according to medical records. Site of EPTB was determined by culture and/or state TB classification. Death was defined by all-cause mortality. Of 1325 eligible reported TB cases, 369 (27·8%) had any EPTB including 258 (19·5%) with only EPTB and 111 (8·4%) with pulmonary TB and EPTB. Of all TB cases, 158 had diabetes (11·9%). In multivariable analysis, the odds of any EPTB was similar in patients with and without diabetes [adjusted odds ratio 1·04, 95% confidence interval (CI) 0·70-1·56]. The risk of death was 23·8% in patients with EPTB and diabetes vs. 9·8% in those with no diabetes (P < 0·01); after adjusting for covariates the difference was not significant (aRR 1·19, 95% CI 0·54-2·63). Diabetes was common in patients with EPTB and risk of death was high. Improved understanding of the relationship between diabetes and EPTB is critical to determine the extent that diabetes affects TB diagnosis and clinical management.
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