ArticleCritical care (London, England)2016
Applying the termination of resuscitation rules to out-of-hospital cardiac arrests of both cardiac and non-cardiac etiologies: a prospective cohort study.
Article in Critical care (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Termination of Resuscitation Rules and Survival Among Patients With Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-Analysis.JAMA network open · 2024Pooled it
- Development of a national consensus guideline for termination of resuscitation in the out-of-hospital environment.British paramedic journal · 2026Article
- Outcomes of Patients From All-Japan Utstein Registry Managed by 2015 Cardiopulmonary Resuscitation Guidelines for Nonshockable Out-of-Hospital Cardiac Arrest.Journal of the American Heart Association · 2026Article
- Resuscitation Attempt and Outcomes in Patients With Asystole Out-of-Hospital Cardiac Arrest.JAMA network open · 2024Article
- The Current Discussion Regarding End-of-Life Care for Patients with Out-of-Hospital Cardiac Arrest with Initial Non-Shockable Rhythm: A Narrative Review.Medicina (Kaunas, Lithuania) · 2024Review
- Predictive performances of ALS and BLS termination of resuscitation rules in out-of-hospital cardiac arrest for different resuscitation protocols.BMC emergency medicine · 2022Article
- Outcomes and interventions in patients transported to hospital with ongoing CPR after out-of-hospital cardiac arrest - An observational study.Resuscitation plus · 2021Article
- A hypothetical implementation of 'Termination of Resuscitation' protocol for out-of-hospital cardiac arrest.Resuscitation plus · 2021Article
- Application of termination of resuscitation rules during the COVID-19 pandemic by emergency medical service.The American journal of emergency medicine · 2021Article
- External validation of multimodal termination of resuscitation rules for out-of-hospital cardiac arrest patients in the COVID-19 era.Scandinavian journal of trauma, resuscitation and emergency medicine · 2021Observational
- Improving Psychological Comfort of Paramedics for Field Termination of Resuscitation through Structured Training.International journal of environmental research and public health · 2021Article
- Best Practices in Managing Cardiac Arrest in the Emergency Department During the COVID-19 Pandemic.Mayo Clinic proceedings · 2020Review
- Mechanical Cardiopulmonary Resuscitation and Hospital Survival Among Adult Patients With Nontraumatic Out-of-Hospital Cardiac Arrest Attending the Emergency Department: A Prospective, Multicenter, Observational Study in Japan (SOS-KANTO [Survey of Survivors after Out-of-Hospital Cardiac Arrest in Kanto Area] 2012 Study).Journal of the American Heart Association · 2017Observational
- Association between cardiopulmonary resuscitation duration and one-month neurological outcomes for out-of-hospital cardiac arrest: a prospective cohort study.BMC anesthesiology · 2017Observational
- Is it possible to terminate resuscitation in accordance with the termination of resuscitation rule?Journal of thoracic disease · 2016Article
- What should we consider when applying termination of resuscitation rules?Journal of thoracic disease · 2016Article
- Should we resuscitate or not-that is the question!Journal of thoracic disease · 2016Article
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Authors and funding
10 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe 2015 American Heart Association Guidelines for Cardiopulmonary Resuscitation recommend Basic Life Support (BLS) and Advanced Life Support (ALS) rules for termination of resuscitation (TOR). However, it is unclear whether the TOR rules are valid for out-of-hospital cardiac arrests (OHCAs) of both cardiac and non-cardiac etiologies. In this study, we validated the TOR rules for OHCA resulting from both etiologies.
methodsThis was a prospective multicenter observational study of OHCA patients transported to 67 emergency hospitals between January 2012 and March 2013 in the Kanto region of Japan. We calculated the specificity and positive predictive value (PPV) for neurologically unfavorable outcomes at one month in patients with OHCA of cardiac and non-cardiac etiologies.
resultsOf 11,505 eligible cases, 6,138 and 5,367 cases were of cardiac and non-cardiac etiology, respectively. BLS was performed on 2,818 and 2,606 patients with OHCA of cardiac and non-cardiac etiology, respectively. ALS was performed on 3,320 and 2,761 patients with OHCA of cardiac and non-cardiac etiology, respectively. The diagnostic accuracy of the TOR rules for predicting unfavorable outcomes in patients with OHCA of cardiac etiology who received BLS included a specificity of 0.985 (95% confidence interval [CI]: 0.956-0.997) and a PPV of 0.999 (95% CI: 0.996-1.000). In patients with OHCA from cardiac etiologies who received ALS, the TOR rules had a specificity of 0.963 (95% CI: 0.896-0.992) and a PPV of 0.997 (95% CI: 0.991-0.999). In patients with OHCA from non-cardiac etiologies who received BLS, the specificity was 0.915 (95% CI: 0.796-0.976) and PPV was 0.998 (95% CI: 0.995-0.999). For patients with OHCA from non-cardiac etiologies who received ALS, the specificity was 0.833 (95% CI: 0.586-0.964) and PPV was 0.996 (95% CI: 0.988-0.999).
conclusionsBoth TOR rules have high specificity and PPV in patients with OHCA from cardiac etiologies. For patients with OHCA from non-cardiac etiologies, the rules had a high PPV, but relatively low specificity. Therefore, TOR rules are useful in patients with OHCA from cardiac etiologies, but should be applied with caution to patients with OHCA from non-cardiac etiologies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.