ArticleScientific reports2016
Detection of Temperature Difference in Neuronal Cells.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed.
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- Internal 3D temperature mapping in biological systems using ratiometric light-sheet imaging and lipid-coated upconversion nanothermometers.Beilstein journal of nanotechnology · 2025Article
- Genetically-encoded temperature indicators for thermal biology.Biophysics and physicobiology · 2025Article
- Heat application in live cell imaging.FEBS open bio · 2024Review
- Optically Active, Paper-Based Scaffolds for 3D Cardiac Pacing.ACS applied materials & interfaces · 2024Article
- Implication of thermal signaling in neuronal differentiation revealed by manipulation and measurement of intracellular temperature.Nature communications · 2024Article
- Thermal properties of nanofluids using hydrophilic and hydrophobic LiYFNanoscale advances · 2024Article
- Temperature-sensing riboceptors.RNA biology · 2024Article
- Article
- Warm Cells, Hot Mitochondria: Achievements and Problems of Ultralocal Thermometry.International journal of molecular sciences · 2023Review
- Niche preclinical and clinical applications of photoacoustic imaging with endogenous contrast.Photoacoustics · 2023Review
- Cell Decision Making through the Lens of Bayesian Learning.Entropy (Basel, Switzerland) · 2023Article
- Heat Release by Isolated Mouse Brain Mitochondria Detected with Diamond Thermometer.Nanomaterials (Basel, Switzerland) · 2022Article
- Spatiotemporally mapping temperature dynamics of lysosomes and mitochondria using cascade organelle-targeting upconversion nanoparticles.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Unusual Mathematical Approaches Untangle Nervous Dynamics.Biomedicines · 2022Review
- A Ratiometric Organic Fluorescent Nanogel Thermometer for Highly Sensitive Temperature Sensing.Biosensors · 2022Article
- Streamlining Culture Conditions for the Neuroblastoma Cell Line SH-SY5Y: A Prerequisite for Functional Studies.Methods and protocols · 2022Article
- Electrical impulse characterization along actin filaments in pathological conditions.Computer physics communications · 2022Article
- Cellular Thermometry Considerations for Probing Biochemical Pathways.Cell biochemistry and biophysics · 2021Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For a better understanding of the mechanisms behind cellular functions, quantification of the heterogeneity in an organism or cells is essential. Recently, the importance of quantifying temperature has been highlighted, as it correlates with biochemical reaction rates. Several methods for detecting intracellular temperature have recently been established. Here we develop a novel method for sensing temperature in living cells based on the imaging technique of fluorescence of quantum dots. We apply the method to quantify the temperature difference in a human derived neuronal cell line, SH-SY5Y. Our results show that temperatures in the cell body and neurites are different and thus suggest that inhomogeneous heat production and dissipation happen in a cell. We estimate that heterogeneous heat dissipation results from the characteristic shape of neuronal cells, which consist of several compartments formed with different surface-volume ratios. Inhomogeneous heat production is attributable to the localization of specific organelles as the heat source.
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