ArticleJournal of computational surgery
Multiscale modeling for clinical translation in neuropsychiatric disease.
Article in Journal of computational surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Calcium regulation of HCN channels supports persistent activity in a multiscale model of neocortex.Neuroscience · 2016Article
- Restoring Behavior via Inverse Neurocontroller in a Lesioned Cortical Spiking Model Driving a Virtual Arm.Frontiers in neuroscience · 2016Article
- Multitarget Multiscale Simulation for Pharmacological Treatment of Dystonia in Motor Cortex.Frontiers in pharmacology · 2016Article
- Computer modeling for pharmacological treatments for dystonia.Drug discovery today. Disease models · 2016Article
- Neuronal calcium wave propagation varies with changes in endoplasmic reticulum parameters: a computer model.Neural computation · 2015Article
- Electrostimulation to reduce synaptic scaling driven progression of Alzheimer's disease.Frontiers in computational neuroscience · 2014Article
- Computer modeling of ischemic stroke.Scholarpedia journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Multiscale modeling of neuropsychiatric illness bridges scales of clinical importance: from the highest scales (presentation of behavioral signs and symptoms), through intermediate scales (clinical testing and surgical intervention), down to the molecular scale of pharmacotherapy. Modeling of brain disease is difficult compared to modeling of other organs, because dysfunction manifests at scales where measurements are rudimentary due both to inadequate access (memory and cognition) and to complexity (behavior). Nonetheless, we can begin to explore these aspects through the use of information-theoretic measures as stand-ins for
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.