ArticleInternational journal of inflammation2016
Investigation of the Anti-Inflammatory and Analgesic Activities of Ethanol Extract of Stem Bark of Sonapatha Oroxylum indicum In Vivo.
Article in International journal of inflammation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 51 citations in OpenAlex.
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- Anti-Inflammatory and Analgesic Activity of Methanolic Root Extract ofJournal of inflammation research · 2022Article
- The application of gargle containing honeysuckle and semen oroxyli to reduce the pain and complications after uvulopalatopharyngoplasty.Frontiers in pharmacology · 2022Article
- Effects of anFrontiers in aging neuroscience · 2021Article
- Systematic Elucidation of the Mechanism ofEvidence-based complementary and alternative medicine : eCAM · 2020Article
- Acute Oral Toxicity and Anti-inflammatory and Analgesic Effects of Aqueous and Methanolic Stem Bark Extracts ofEvidence-based complementary and alternative medicine : eCAM · 2020Article
- Antioxidant, Anti-Inflammatory, and Analgesic Activities of Aqueous Extract ofTheScientificWorldJournal · 2020Article
- Animal Models of Inflammation for Screening of Anti-inflammatory Drugs: Implications for the Discovery and Development of Phytopharmaceuticals.International journal of molecular sciences · 2019Review
- Ethnopharmacological Inspections of Organic Extract ofEvidence-based complementary and alternative medicine : eCAM · 2019Article
- Anti-inflammatory hybrids of secondary amines and amide-sulfamide derivatives.European journal of medicinal chemistry · 2018Article
- Antimelanogenic Effect of an Oroxylum indicum Seed Extract by Suppression of MITF Expression through Activation of MAPK Signaling Protein.International journal of molecular sciences · 2018Article
- Study of analgesic effect of earthworm extract.Bioscience reports · 2018Article
- Novel anti-inflammatory agents targeting CXCR4: Design, synthesis, biological evaluation and preliminary pharmacokinetic study.European journal of medicinal chemistry · 2017Article
- Hydro-ethanolic leaf extract of Ziziphus abyssinica Hochst Ex A. Rich (Rhamnaceae) exhibits anti-nociceptive effects in murine models.BMC complementary and alternative medicine · 2017Article
- Development of CXCR4 modulators by virtual HTS of a novel amide-sulfamide compound library.European journal of medicinal chemistry · 2017Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inflammation is all a pervasive phenomenon, which is elicited by the body in response to obnoxious stimuli as a protective measure. However, sustained inflammation leads to several diseases including cancer. Therefore it is necessary to neutralize inflammation. Sonapatha (Oroxylum indicum), a medicinal plant, is traditionally used as a medicine in Ayurveda and other folk systems of medicine. It is commonly used to treat inflammatory diseases including rheumatoid arthritis and asthma. Despite this fact its anti-inflammatory and analgesic effects are not evaluated scientifically. Therefore, the anti-inflammatory and analgesic activities of Sonapatha (Oroxylum indicum) were studied in Swiss albino mice by different methods. The hot plate, acetic acid, and tail immersion tests were used to evaluate the analgesic activity whereas xylene-induced ear edema and formalin induced paw edema tests were used to study the anti-inflammatory activity of Sonapatha. The administration of mice with 250 and 300 mg/kg b.wt. of O. indicum reduced pain and inflammation indicating that Sonapatha possesses analgesic and anti-inflammatory activities. The maximum analgesic and anti-inflammatory activities were observed in mice receiving 300 mg/kg b.wt. of O. indicum ethanol extract. Our study indicates that O. indicum possesses both anti-inflammatory and analgesic activities and it may be useful as an anti-inflammatory agent in the inflammation related disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.