ArticleArchives of medical science : AMS2016
Correlation of iron deposition and change of gliocyte metabolism in the basal ganglia region evaluated using magnetic resonance imaging techniques: an in vivo study.
Article in Archives of medical science : AMS, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- The amplitude of low frequency fluctuation and spontaneous brain activity alterations in age-related macular degeneration.Frontiers in medicine · 2024Article
- Susceptibility phase imaging of deep gray matter: Presenting the effects of slice orientation.The neuroradiology journal · 2023Article
- ATP13A2 protects dopaminergic neurons in Parkinson's disease: from biology to pathology.Journal of biomedical research · 2022Article
- Altered spontaneous brain activity patterns in patients with diabetic retinopathy using amplitude of low-frequency fluctuation.World journal of diabetes · 2022Article
- Altered Spontaneous Brain Activity Patterns of Meibomian Gland Dysfunction in Severely Obese Population Measured Using the Fractional Amplitude of Low-Frequency Fluctuations.Frontiers in psychiatry · 2022Article
- Lab-on-Chip Microsystems forFrontiers in bioengineering and biotechnology · 2022Review
- The predictive potential of altered spontaneous brain activity patterns in diabetic retinopathy and nephropathy.The EPMA journal · 2019Article
- Altered brain network centrality in patients with late monocular blindness: a resting-state fMRI study.Archives of medical science : AMS · 2019Article
- Altered spontaneous brain activity patterns in patients with corneal ulcer using amplitude of low-frequency fluctuation: An fMRI study.Experimental and therapeutic medicine · 2019Article
- Observational
- Neurochemical changes in the hippocampus and prefrontal cortex associated with electroacupuncture for learning and memory impairment.International journal of molecular medicine · 2018Article
- Augmented mitochondrial cytochrome c oxidase activity in children with iron deficiency: a tandem between iron and copper?Archives of medical science : AMS · 2018Article
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2 authors.
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Abstract
introductionWe assessed the correlation between iron deposition and the change of gliocyte metabolism in healthy subjects' basal ganglia region, by using 3D-enhanced susceptibility weighted angiography (ESWAN) and proton magnetic resonance spectroscopy ((1)H-MRS). MATERIAL AND
methodsSeventy-seven healthy volunteers (39 female and 38 male subjects; age range: 24-82 years old) were enrolled in the experiment including ESWAN and proton MRS sequences, consent for which was provided by themselves or their guardians. For each subject, the mean phase value gained by ESWAN was used to evaluate the iron deposition; choline/creatine (Cho/Cr) and mI/Cr ratios gained by (1)H-MRS were used to evaluate gliocyte metabolism in the basal ganglia region of both sides. The paired t test was used to test the difference between the two sides of the basal ganglia region. Linear regression was performed to evaluate the relation between mean phase value and age. Pearson's correlation coefficient was calculated to analyze the relationship between the result of ESWAN and (1)H-MRS.
resultsThere was no difference between the two sides of the basal ganglia region in the mean phase value and Cho/Cr. But in mI/Cr the mean phase value of each nucleus in bilateral basal ganglia decreased with increasing age. There are 16 r-values between the mean phase value and Cho/Cr and mI/Cr in bilateral basal ganglia region. And each of all p-values is less than 0.001 (p < 0.001).
conclusionsIron deposition in the bilateral basal ganglia is associated with the change of gliocyte metabolism with increasing age. Iron deposition in each nucleus of the basal ganglia region changes with age.
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