ArticleFrontiers in plant science2016
Global Metabolic Profiling of Arabidopsis Polyamine Oxidase 4 (AtPAO4) Loss-of-Function Mutants Exhibiting Delayed Dark-Induced Senescence.
Article in Frontiers in plant science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- The Metabolic Profile of Young, Watered Chickpea Plants Can Be Used as a Biomarker to Predict Seed Number under Terminal Drought.Plants (Basel, Switzerland) · 2023Article
- An Undefined Interaction between Polyamines and Heat Shock Proteins Leads to Cellular Protection inMolecules (Basel, Switzerland) · 2023Review
- GUS Reporter-Aided Promoter Deletion Analysis ofInternational journal of molecular sciences · 2023Article
- Polyamine Oxidase-Generated Reactive Oxygen Species in Plant Development and Adaptation: The Polyamine Oxidase-NADPH Oxidase Nexus.Antioxidants (Basel, Switzerland) · 2022Review
- Versatile roles of polyamines in improving abiotic stress tolerance of plants.Frontiers in plant science · 2022Review
- Primary metabolic processes as drivers of leaf ageing.Cellular and molecular life sciences : CMLS · 2021Review
- Cadaverine regulates biotin synthesis to modulate primary root growth in Arabidopsis.The Plant journal : for cell and molecular biology · 2021Article
- IntegratedFrontiers in plant science · 2021Article
- Article
- Biologia futura: the role of polyamine in plant science.Biologia futura · 2020Review
- Spermine-priming restrained water relations and biochemical deteriorations prompted by water deficit on two soybean cultivars.Heliyon · 2020Article
- Foliar Application of Polyamines Modulates Winter Oilseed Rape Responses to Increasing Cold.Plants (Basel, Switzerland) · 2020Article
- Polyamine Oxidases Play Various Roles in Plant Development and Abiotic Stress Tolerance.Plants (Basel, Switzerland) · 2019Review
- Polyamines - A New Metabolic Switch: Crosstalk With Networks Involving Senescence, Crop Improvement, and Mammalian Cancer Therapy.Frontiers in plant science · 2019Article
- Spermine Differentially Refines Plant Defense Responses Against Biotic and Abiotic Stresses.Frontiers in plant science · 2019Review
- Polyamine Function in Plants: Metabolism, Regulation on Development, and Roles in Abiotic Stress Responses.Frontiers in plant science · 2018Review
- Polyamine catabolism adds fuel to leaf senescence.Amino acids · 2017Review
- Copper-Containing Amine Oxidases and FAD-Dependent Polyamine Oxidases Are Key Players in Plant Tissue Differentiation and Organ Development.Frontiers in plant science · 2016Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early and more recent studies have suggested that some polyamines (PAs), and particularly spermine (Spm), exhibit anti-senescence properties in plants. In this work, we have investigated the role of Arabidopsis Polyamine Oxidase 4 (PAO4), encoding a PA back-conversion oxidase, during dark-induced senescence. Two independent PAO4 (pao4-1 and pao4-2) loss-of-function mutants have been found that accumulate 10-fold higher Spm, and this associated with delayed entry into senescence under dark conditions. Mechanisms underlying pao4 delayed senescence have been studied using global metabolic profiling by GC-TOF/MS. pao4 mutants exhibit constitutively higher levels of important metabolites involved in redox regulation, central metabolism and signaling that support a priming status against oxidative stress. During senescence, interactions between PAs and oxidative, sugar and nitrogen metabolism have been detected that additively contribute to delayed entry into senescence. Our results indicate the occurrence of metabolic interactions between PAs, particularly Spm, with cell oxidative balance and transport/biosynthesis of amino acids as a strategy to cope with oxidative damage produced during senescence.
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