Evidence map›Paper›PMID 26924964›Full record

ArticleFrontiers in neural circuits2016

Stimulus Contrast and Retinogeniculate Signal Processing.

Daniel L Rathbun, Henry J Alitto, David K Warland, W Martin Usrey

Abstract read
In one paragraph

Article in Frontiers in neural circuits, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Differential Impact of Retinal Lesions on Visual Responses of LGN X and Y Cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. The Augmentation of Retinogeniculate Communication during Thalamic Burst Mode.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Article
  7. Contrast gain control and retinogeniculate communication.The European journal of neuroscience · 2019
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Retinal and Nonretinal Contributions to Extraclassical Surround Suppression in the Lateral Geniculate Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017
    Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Daniel L RathbunCenter for Neuroscience, University of CaliforniaDavis, Davis, CA, USA; Institute for Ophthalmology and Center for Integrative Neuroscience, University of TübingenTübingen, Germany.
Henry J AlittoCenter for Neuroscience, University of CaliforniaDavis, Davis, CA, USA; Department of Neurobiology, Physiology, and Behavior, University of CaliforniaDavis, Davis, CA, USA.
David K WarlandCenter for Neuroscience, University of CaliforniaDavis, Davis, CA, USA; Department of Neurobiology, Physiology, and Behavior, University of CaliforniaDavis, Davis, CA, USA.
W Martin UsreyCenter for Neuroscience, University of CaliforniaDavis, Davis, CA, USA; Department of Neurobiology, Physiology, and Behavior, University of CaliforniaDavis, Davis, CA, USA.

Funding

VISION RESEARCH CORE GRANTP30EY012576 · NEI · UNIVERSITY OF CALIFORNIA DAVIS · PI MARIE E BURNS · 1999 to 2026
$18.9M
Functional Properties of Neural Circuits for VisionR01EY013588 · NEI · UNIVERSITY OF CALIFORNIA DAVIS · PI USREY, W MARTIN · 2001 to 2022
$7.8M
Vision Science Training Program: Cornea to CortexT32EY015387 · NEI · UNIVERSITY OF CALIFORNIA DAVIS · PI MARIE E BURNS · 2003 to 2026
$4.8M
NEI NIH HHS EY12576NEI NIH HHS EY13588NEI NIH HHS T32EY15387
6 · The paper itself

Abstract

Neuronal signals conveying luminance contrast play a key role in nearly all aspects of perception, including depth perception, texture discrimination, and motion perception. Although much is known about the retinal mechanisms responsible for encoding contrast information, relatively little is known about the relationship between stimulus contrast and the processing of neuronal signals between visual structures. Here, we describe simultaneous recordings from monosynaptically connected retinal ganglion cells and lateral geniculate nucleus (LGN) neurons in the cat to determine how stimulus contrast affects the communication of visual signals between the two structures. Our results indicate that: (1) LGN neurons typically reach their half-maximal response at lower contrasts than their individual retinal inputs and (2) LGN neurons exhibit greater contrast-dependent phase advance (CDPA) than their retinal inputs. Further analyses suggests that increased sensitivity relies on spatial convergence of multiple retinal inputs, while increased CDPA is achieved, in part, on temporal summation of arriving signals.

Indexed as

Action PotentialsAnimalsBrain MappingCatsContrast SensitivityElectrocardiographyElectroencephalographyFemaleGeniculate BodiesMaleModels, BiologicalPhotic StimulationRetinaSensory Receptor CellsVisual PathwayscodingLGNretinathalamusvision

Identifiers

PMID26924964
PMCPMC4759309

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.