Evidence map›Paper›PMID 26924655›Full record

ArticleScientific reports2016

Questioning the role of the frontopolar cortex in multi-component behavior--a TMS/EEG study.

Krutika Gohil, Gabriel Dippel, Christian Beste

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Krutika GohilCognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine of the TU Dresden, Germany.
Gabriel DippelCognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine of the TU Dresden, Germany.
Christian BesteCognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine of the TU Dresden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive control is central to many every day situations. There, we usually have to combine different actions to achieve a task goal. Several lines of research indicated that areas in the prefrontal cortex determine cognitive control in situations requiring multi-component behavior. One of this is the frontopolar cortex (FPC). However, direct non-correlative evidence for this notion is widely lacking. In the current study we test the importance of the FPC for the implementation of action cascading processes in a TMS/EEG study. The data, however, clearly show that the FPC does not modulate behavioral or neurophysiological parameters reflecting action cascading, which is in contrast to the findings of dorsolateral prefrontal cortex. The results are supported by a Bayesian analysis of the data. The results suggest that a possible role of the FPC in multi-component behavior needs to be refined. At least in situations, where multi-component behavior is achieved by stopping and switching processes and does not impose high demands on working memory processes the FPC seems to play no role in the implementation of this major cognitive control function.

Indexed as

CognitionAnalysis of VarianceAttentionElectroencephalographyEvent-Related Potentials, P300Evoked Potentials, MotorFemaleHumansMagnetic Resonance ImagingMaleNeuropsychological TestsPerceptionPrefrontal CortexReaction Time

Identifiers

PMID26924655
PMCPMC4770427

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.