ArticleScientific reports2016
Cobalt oxide nanoparticles can enter inside the cells by crossing plasma membranes.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- A simple microplasma reactor paired with indirect ultrasonication for aqueous phase synthesis of cobalt oxide nanoparticles.Nanoscale advances · 2023Article
- The "www" ofMembranes · 2022Review
- Exposure of Metal Oxide Nanoparticles on the Bioluminescence Process ofNanomaterials (Basel, Switzerland) · 2021Article
- Comparisons of the Effect of Different Metal Oxide Nanoparticles on the Root and Shoot Growth under Shaking and Non-Shaking Incubation, Different Plants, and Binary Mixture Conditions.Nanomaterials (Basel, Switzerland) · 2021Article
- Cobalt oxide nanoparticles induce oxidative stress and alter electromechanical function in rat ventricular myocytes.Particle and fibre toxicology · 2021Article
- Novel Approaches of Dysregulating Lysosome Functions in Cancer Cells by Specific Drugs and Its Nanoformulations: A Smart Approach of Modern Therapeutics.International journal of nanomedicine · 2021Review
- Evaluation of the Effects of Particle Sizes of Silver Nanoparticles on Various Biological Systems.International journal of molecular sciences · 2020Article
- Comparative Effects of Particle Sizes of Cobalt Nanoparticles to Nine Biological Activities.International journal of molecular sciences · 2020Article
- Article
- Biophysical Characterization of (Silica-coated) Cobalt Ferrite Nanoparticles for Hyperthermia Treatment.Nanomaterials (Basel, Switzerland) · 2019Article
- Multi-walled carbon nanotubes upregulate mitochondrial gene expression and trigger mitochondrial dysfunction in primary human bronchial epithelial cells.Nanotoxicology · 2019Article
- Nano-delivery of trace minerals for marine fish larvae: influence on skeletal ossification, and the expression of genes involved in intestinal transport of minerals, osteoblast differentiation, and oxidative stress response.Fish physiology and biochemistry · 2018Article
- The Detailed Bactericidal Process of Ferric Oxide Nanoparticles on E. coli.Molecules (Basel, Switzerland) · 2018Article
- Transporting carriers for intracellular targeting delivery via non-endocytic uptake pathways.Drug delivery · 2017Review
- Effects of Metal Micro and Nano-Particles on hASCs: An In Vitro Model.Nanomaterials (Basel, Switzerland) · 2017Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ability of nanoparticles (NPs) to be promptly uptaken by the cells makes them both dangerous and useful to human health. It was recently postulated that some NPs might cross the plasma membrane also by a non-endocytotic pathway gaining access to the cytoplasm. To this aim, after having filled mature Xenopus oocytes with Calcein, whose fluorescence is strongly quenched by divalent metal ions, we have exposed them to different cobalt NPs quantifying quenching as evidence of the increase of the concentration of Co(2+) released by the NPs that entered into the cytoplasm. We demonstrated that cobalt oxide NPs, but not cobalt nor cobalt oxide NPs that were surrounded by a protein corona, can indeed cross plasma membranes.
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