ArticleNeuron2016
Functional Segregation of Cortical Regions Underlying Speech Timing and Articulation.
Article in Neuron, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
86 citing papers in PubMed.
- Crowdsourced Perceptual Ratings of Voice Quality in People With Parkinson's Disease Before and After Intensive Voice and Articulation Therapies: Secondary Outcome of a Randomized Controlled Trial.Journal of speech, language, and hearing research : JSLHR · 2023Trial
- Noninvasive neurostimulation of left ventral motor cortex enhances sensorimotor adaptation in speech production.Brain and language · 2020Trial
- Brain-AI convergence: Generative world models and hierarchical attention for human intelligence.Patterns (New York, N.Y.) · 2026Review
- Human cortex organizes dynamic co-fluctuations along the sensorimotor-association axis.Nature communications · 2026Article
- Article
- Mild Focal Cooling Decouples Dendrites to Reconfigure Cortical Output.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Brain maintenance biomarkers from structural and functional interactions in aging and neurodegeneration.Nature communications · 2026Article
- Temperature robustness of the timing network within songbird premotor nucleus HVC.Journal of computational neuroscience · 2026Article
- Neural activity flows through cortical subnetworks during speech production.Cell reports · 2026Article
- Speech sequencing in the human precentral gyrus.Nature human behaviour · 2025Article
- Article
- Age-Associated Cortical Thinning in Speech Motor Regions Precedes Hippocampal Decline: Implications for Alzheimer's Disease.Human brain mapping · 2025Article
- Lateralized local circuit tuning in female mouse auditory cortex.Neuroscience research · 2025Article
- Frontal-auditory cortical interactions and sensory prediction during vocal production in marmoset monkeys.Current biology : CB · 2025Article
- Inhibitory control of speech production in the human premotor frontal cortex.Nature human behaviour · 2025Article
- Article
- Perineuronal nets in motor circuitry regulate the performance of learned vocalizations in songbirds.Communications biology · 2025Article
- Investigating the role of the left inferior frontal gyrus in language evolution: insights from comparative neuroscience.Frontiers in human neuroscience · 2025Review
- Wernicke's functional neuroanatomy model of language turns 150: what became of its psychological reflex arcs?Brain structure & function · 2024Review
- Stimulation of caudal inferior and middle frontal gyri disrupts planning during spoken interaction.Current biology : CB · 2024Article
26 more citing papers are in PubMed but not listed here.
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Authors and funding
9 authors.
Funding
Abstract
Spoken language is a central part of our everyday lives, but the precise roles that individual cortical regions play in the production of speech are often poorly understood. To address this issue, we focally lowered the temperature of distinct cortical regions in awake neurosurgical patients, and we relate this perturbation to changes in produced speech sequences. Using this method, we confirm that speech is highly lateralized, with the vast majority of behavioral effects seen on the left hemisphere. We then use this approach to demonstrate a clear functional dissociation between nearby cortical speech sites. Focal cooling of pars triangularis/pars opercularis (Broca's region) and the ventral portion of the precentral gyrus (speech motor cortex) resulted in the manipulation of speech timing and articulation, respectively. Our results support a class of models that have proposed distinct processing centers underlying motor sequencing and execution for speech.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.