Evidence map›Paper›PMID 26924008›Full record

ArticleScientific reports2016

Low serum calcium is associated with left ventricular systolic dysfunction in a Chinese population with coronary artery disease.

Yong Wang, Heng Ma, Xiaochen Hao, Jun Yang, Qiujing Chen, Lin Lu, Ruiyan Zhang

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Yong WangDepartment of Cardiology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Heng MaYuhuangding Hospital, Qingdao University School of Medicine, Yantai 264000, China.
Xiaochen HaoDepartment of Cardiology, Anqiu People's Hospital, Weifang 261000, China.
Jun YangYuhuangding Hospital, Qingdao University School of Medicine, Yantai 264000, China.
Qiujing ChenDepartment of Cardiology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Lin LuDepartment of Cardiology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Ruiyan ZhangDepartment of Cardiology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Ruijin Hospital · CNShanghai Jiao Tong University · CNQingdao University · CNWeifang People's Hospital · CNYuhuangding Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Whether serum calcium is associated with heart systolic function in patients with established coronary artery disease (CAD) and acute myocardial infarction (AMI) remains to be elucidated. This study is aimed to assess the association between serum calcium and left ventricular systolic dysfunction in a Chinese population of CAD. The cross-sectional study included 5938 CAD patients with and without AMI in China. The factors associated with AMI and left ventricular ejection fraction (LVEF) were evaluated. The data showed that AMI patients had lower serum calcium levels (2.11 ± 0.13 vs 2.20 ± 0.10 mmol/l, P < 0.001) than those without AMI. Multiple logistic regression analysis exhibited that serum calcium (OR: 0.000, 95% CI: 0.000-0.001) was one of the independent factors correlated with AMI. CAD patients with and without AMI when LVEF <50% had lower serum calcium levels than those when LVEF ≥50% respectively. Serum calcium was independently associated with LVEF and LVEF <50% in CAD patients with and without AMI respectively using multivariate analysis. The independent association between serum calcium and LVEF still existed among CAD patients when LVEF ≥50%. Serum calcium levels are significantly decreased following AMI. Low serum calcium is independently correlated with left ventricular systolic dysfunction in CAD patients with and without AMI.

Indexed as

AgedAsian PeopleBiomarkersCalciumChinaComorbidityCoronary Artery DiseaseFemaleHumansMaleMiddle AgedRisk FactorsStroke VolumeVentricular Dysfunction, LeftBiomarkersCalcium

Identifiers

PMID26924008
PMCPMC4770278
OpenAlexW2318641702

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.