ArticleDigestive diseases and sciences2016
Successful Endoscopic Hemostasis Is a Protective Factor for Rebleeding and Mortality in Patients with Nonvariceal Upper Gastrointestinal Bleeding.
Article in Digestive diseases and sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- Comparison of TC-325 Hemostatic Powder with Standard Endoscopic Treatments for Malignancy-Related Upper Gastrointestinal Bleeding: Meta-Analysis of Randomized Controlled Trials.Digestive diseases and sciences · 2024Pooled it
- Predictors and Outcomes of Nonvariceal Upper Gastrointestinal Bleed After Coronary Artery Bypass Grafting: A Nationwide Analysis.Journal of the American Heart Association · 2026Article
- Changing Epidemiology and Etiology of Upper Gastrointestinal Bleeding.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025Review
- Analysis of factors associated with 1-year rebleeding in patients with acute upper gastrointestinal bleeding and a Glasgow- Blatchford Score ≥ 6 based on serological indicators.Frontiers in medicine · 2025Article
- Ulcer Bleeding in the United States: Epidemiology, Treatment Success, and Resource Utilization.Digestive diseases and sciences · 2024Article
- Role of second look endoscopy in endoscopic submucosal dissection and peptic ulcer bleeding: Meta-analysis of randomized controlled trials.World journal of gastrointestinal endoscopy · 2024Article
- Features of patients with upper gastrointestinal bleeding and factors affecting the re-bleeding risk.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- Over-the-scope clip as first-line therapy for ulcers with high-risk bleeding stigmata is efficient compared to standard endoscopic therapy.Endoscopy international open · 2021Article
- Biopsy in emergency gastroscopy does not increase the risk of rebleeding in patients with Forrest I acute nonvariceal upper gastrointestinal bleeding combined with suspected malignant gastric ulcer: a multicenter retrospective cohort study.BMC gastroenterology · 2021Article
- Prealbumin and D-dimer as Prognostic Indicators for Rebleeding in Patients with Nonvariceal Upper Gastrointestinal Bleeding.Digestive diseases and sciences · 2021Article
- Over-The-Scope Clip system as a first-line therapy for high-risk bleeding peptic ulcers: a retrospective study.Surgical endoscopy · 2021Observational
- Safety and Efficacy of the Noncessation Method of Antithrombotic Agents after Emergency Endoscopic Hemostasis in Patients with Nonvariceal Upper Gastrointestinal Bleeding: A Multicenter Pilot Study.Canadian journal of gastroenterology & hepatology · 2021Article
- Potential role of new technological innovations in nonvariceal hemorrhage.World journal of gastrointestinal endoscopy · 2019Article
- First-line endoscopic treatment with over-the-scope clips significantly improves the primary failure and rebleeding rates in high-risk gastrointestinal bleeding: A single-center experience with 100 cases.World journal of gastroenterology · 2016Observational
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRebleeding and mortality rates remain high in patients with nonvariceal upper gastrointestinal bleeding.
aimTo identify clinical and endoscopic risk factors for rebleeding and mortality in patients with nonvariceal upper gastrointestinal bleeding.
methodsThis study was performed in patients with nonvariceal upper gastrointestinal bleeding who underwent upper endoscopic procedures between July 2006 and February 2013. Clinical and endoscopic characteristics were compared among patients with and without rebleeding and mortality. Logistic regression analysis was performed to determine independent risk factors for rebleeding and mortality.
resultsAfter excluding 64 patients, data for 689 patients with nonvariceal upper gastrointestinal bleeding were analyzed. Peptic ulcer (62.6 %) was by far the most common source of bleeding. Endoscopic intervention was performed within 24 h in 99.0 % of patients, and successful endoscopic hemostasis was possible in 80.7 % of patients. The 30-day rebleeding rate was 13.1 % (n = 93). Unsuccessful endoscopic hemostasis was found to be the only independent risk factor for rebleeding (odds ratio 79.6; 95 % confidence interval 37.8-167.6; p = 0.000). The overall 30-day mortality rate was 3.2 % (n = 23). Unsuccessful endoscopic hemostasis (odds ratio 4.9; 95 % confidence interval 1.7-13.9; p = 0.003) was also associated with increased 30-day mortality in patients with nonvariceal upper gastrointestinal bleeding.
conclusionsSuccessful endoscopic hemostasis is an independent protective factor for both rebleeding and mortality in patients with nonvariceal upper gastrointestinal bleeding.
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