ArticleNeurologia medico-chirurgica2016
Bilateral Chronic Subdural Hematoma is Associated with Rapid Progression and Poor Clinical Outcome.
Article in Neurologia medico-chirurgica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06337851 (Comparing Simultaneous and Consecutive Drainage of Bilateral Chronic Subdural Hematoma), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparing Simultaneous and Consecutive Drainage of Bilateral Chronic Subdural Hematoma
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Subperiosteal/subgaleal drainage vs. subdural drainage for chronic subdural hematoma: A meta-analysis of postoperative outcomes.PloS one · 2023Pooled it
- Simultaneous and Consecutive Drainage of Bilateral Chronic Subdural Hematoma: A Randomized Controlled Trial.Neurologia medico-chirurgica · 2024Trial
- Comparison of Bilateral and Unilateral Chronic Subdural Hematomas: A Retrospective Multi-institutional Cohort Study.Neurosurgery practice · 2026Article
- Warfarin-associated Chronic Subdural Hematomas May Exhibit a Shorter Post-traumatic Interval: An Observational Study.Neurologia medico-chirurgica · 2026Observational
- Delayed evacuation of bilateral chronic subdural hematoma with herniation-induced bilateral posterior cerebral artery infarction: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Age-Related Comparative Study of In-Hospital Mortality, Functional Outcome, and Recurrence in a Large Cohort of Patients Surgically Treated for Chronic Subdural Hematoma.Journal of clinical medicine · 2025Article
- Contralateral Progression after Unilateral Surgery for Bilateral Chronic Subdural Hematoma: A Prospective Observational Study.Neurologia medico-chirurgica · 2025Observational
- Prognostic significance of systemic inflammation response index, systemic immune-inflammation index and neutrophil-to-lymphocyte ratio in patients with chronic subdural hematoma after burr hole drainage.Frontiers in neurology · 2025Article
- Management of Antithrombotic Drugs in Patients with Isolated Traumatic Brain Injury: An Intersociety Consensus Document.Neurocritical care · 2024Article
- Development of machine learning models for predicting unfavorable functional outcomes from preoperative data in patients with chronic subdural hematomas.Scientific reports · 2023Article
- Letter to the editor: Effect of postoperative tranexamic acid on recurrence rate and complications in chronic subdural hematomas patients: preliminary results of a randomized controlled clinical trial.Neurosurgical review · 2023Article
- The effect of antithrombotic therapy on the recurrence and outcome of chronic subdural hematoma after burr-hole craniostomy in a population-based cohort.Acta neurochirurgica · 2022Article
- Middle Meningeal Artery Embolization for the Treatment of Bilateral Chronic Subdural Hematoma.Frontiers in neurology · 2021Article
- Not Everything Requires a Psychiatry Consult: Subdural Hematoma as a Cause of Transient Acute Quadriplegia.Cureus · 2020Article
- Acute on Chronic Bilateral Subdural Hematoma in a Woman with a Remote History of Previous Subdural Hematoma Managed by Trephination: A Case Report.JNMA; journal of the Nepal Medical Association · 2020Article
- Outcomes following surgery in subgroups of comatose and very elderly patients with chronic subdural hematoma.Neurosurgical review · 2019Article
- Clinical investigation of chronic subdural hematoma with impending brain herniation on arrival.Neurosurgical review · 2018Article
- Chronic Subdural Hematoma in Elderly Patients: Is This Disease Benign?Neurologia medico-chirurgica · 2017Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic subdural hematoma (CSDH) has been recognized as a benign disease, but its clinical outcome is not well documented. This study aims to expand the knowledge base regarding the outcome of CSDH. We retrospectively reviewed clinical characteristics of CSDH operated in the Kobe City Medical Center General Hospital between June 2005 and June 2012. Variants included age at onset, sex, laterality, presence of headache, consciousness level, and risk factors for hemorrhage such as malignancy or intake of anticoagulants. A total of 368 cases were analyzed. Six patients (1.4%) had a poor outcome, defined as any morbidity or mortality at 7 days postoperatively. Bilateral hematoma was significantly associated with a poor outcome (p = 0.041). Warfarin use and malignancy, albeit statistically not significant, were more frequently observed in patients with a poor outcome. Bilateral CSDH was observed in 53 patients (14.4%). Age at onset, sex, history of malignancy, anticoagulant use, and antiplatelet use did not differ between bilateral and unilateral CSDH. Recurrence rate was not different between bilateral and unilateral CSDH (14.2% vs. 11.3%), but poor outcome as a result of brain herniation was significantly higher in bilateral than in unilateral hematomas (5.7% vs. 0.3%, p = 0.01). Bilateral CSDH was associated with rapid progression and showed worse outcome as a result of brain herniation in comparison with unilateral CSDH. Urgent trephination surgery for decompression of hematoma pressure may be recommended for bilateral CSDH.
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