Evidence map›Paper›PMID 26923433›Full record

ReviewBiochimica et biophysica acta2016

Imaging of myocardial fatty acid oxidation.

Kieren J Mather, Timothy R DeGrado

Abstract readReview
In one paragraph

Review in Biochimica et biophysica acta, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Synthesis and Preliminary Evaluation of anMolecular imaging and biology · 2023
    Article
  4. GPER-dependent estrogen signaling increases cardiac GCN5L1 expression.American journal of physiology. Heart and circulatory physiology · 2022
    Article
  5. Review
  6. PET imaging of glucose and fatty acid metabolism for NAFLD patients.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  7. Review
  8. Dynamic cardiac PET imaging: Technological improvements advancing future cardiac health.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  9. Review
  10. Article
  11. Article
  12. Radiation induced oxidation of [Nuclear medicine and biology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kieren J MatherDepartment of Medicine, Indiana University Medical Center, Gatch Hall, Suite 365, 1120 W. Michigan St., Indianapolis, IN 46202-5111, USA. Electronic address: kmather@iu.edu.
Timothy R DeGradoDepartment of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. Electronic address: degrado.timothy@mayo.edu.

Funding

ZOSUQUIDAR TRIHYDROCHLORIDE DURING CONVENTIONAL INDUCTION AND POST-REMISSIONM01RR000750 · NCRR · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI TISDALE, JAMES E. · 1985 to 2008
$25.5M
Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
Translation CoreP30DK097512 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Carmella Evans-Molina · 2015 to 2026
$17.4M
Indiana Clinical and Translational Science Institute (UL1)UL1TR000006 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI SHEKHAR, ANANTHA · 2012 to 2013
$5.6M
Cardiovascular effects of GLP-1 in obesity/metabolic syndromeR01HL117620 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI MATHER, KIEREN J, TUNE, JOHNATHAN D · 2013 to 2017
$3.4M
PET Approach To Measuring Human Myocardial MetabolismR21DK071142 · NIDDK · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI MATHER, KIEREN J · 2005 to 2006
$409k
NCATS NIH HHS UL1 TR000006NCATS NIH HHS UL1 TR001108NCRR NIH HHS M01 RR000750NHLBI NIH HHS R01 HL117620NIDDK NIH HHS P30 DK097512NIDDK NIH HHS R21 DK071142
6 · The paper itself

Abstract

Myocardial fuel selection is a key feature of the health and function of the heart, with clear links between myocardial function and fuel selection and important impacts of fuel selection on ischemia tolerance. Radiopharmaceuticals provide uniquely valuable tools for in vivo, non-invasive assessment of these aspects of cardiac function and metabolism. Here we review the landscape of imaging probes developed to provide non-invasive assessment of myocardial fatty acid oxidation (MFAO). Also, we review the state of current knowledge that myocardial fatty acid imaging has helped establish of static and dynamic fuel selection that characterizes cardiac and cardiometabolic disease and the interplay between fuel selection and various aspects of cardiac function. This article is part of a Special Issue entitled: Heart Lipid Metabolism edited by G.D. Lopaschuk.

Indexed as

Imaging, Three-DimensionalAnimalsCardiovascular DiseasesFatty AcidsHumansMyocardiumOxidation-ReductionRadiopharmaceuticalsFatty AcidsRadiopharmaceuticalsFatty acid oxidationFatty acid uptakeMetabolic imagingMyocardial metabolismPETSPECT

Identifiers

PMID26923433
PMCPMC5141514

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.