ReviewNature reviews. Microbiology2016
A new view into prokaryotic cell biology from electron cryotomography.
Review in Nature reviews. Microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed.
- Integrating in situ single-particle cryo-electron microscopy with cryo-electron tomography for high-resolution structural biology in native cellular contexts.Current opinion in structural biology · 2026Review
- Structural biology inside multicellular specimens using electron cryotomography.Quarterly reviews of biophysics · 2025Review
- A widespread bacterial protein compartment sequesters and stores elemental sulfur.Science advances · 2024Article
- Structures and Efflux Mechanisms of the AcrAB-TolC Pump.Sub-cellular biochemistry · 2024Article
- Accurate real space iterative reconstruction (RESIRE) algorithm for tomography.Scientific reports · 2023Article
- Live-Cell Fluorescence Imaging of Magnetosome Organelle for Magnetotaxis Motility.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Article
- In Situ Structure Determination of Bacterial Surface Nanomachines Using Cryo-Electron Tomography.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Bridging nano- and microscale X-ray tomography for battery research by leveraging artificial intelligence.Nature nanotechnology · 2022Review
- Practices for running a research-oriented shared cryo-EM facility.Frontiers in molecular biosciences · 2022Article
- A cryo-electron tomography workflow reveals protrusion-mediated shedding on injured plasma membrane.Science advances · 2021Article
- Article
- Effects of antimicrobial photodynamic therapy on antibiotic-resistant Escherichia coli.Photodiagnosis and photodynamic therapy · 2020Article
- A unified framework for packing deformable and non-deformable subcellular structures in crowded cryo-electron tomogram simulation.BMC bioinformatics · 2020Article
- A simulated annealing approach for resolution guided homogeneous cryo-electron microscopy image selection.Quantitative biology (Beijing, China) · 2020Article
- In vivo structure of the Legionella type II secretion system by electron cryotomography.Nature microbiology · 2019Article
- Enabling technologies in super-resolution fluorescence microscopy: reporters, labeling, and methods of measurement.Current opinion in structural biology · 2019Review
- The molecular architecture of engulfment duringeLife · 2019Article
- The Gram-Positive Bacterial Cell Wall.Microbiology spectrum · 2019Review
- From Atoms to Cells: Using Mesoscale Landscapes to Construct Visual Narratives.Journal of molecular biology · 2018Review
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
Abstract
Electron cryotomography (ECT) enables intact cells to be visualized in 3D in an essentially native state to 'macromolecular' (∼4 nm) resolution, revealing the basic architectures of complete nanomachines and their arrangements in situ. Since its inception, ECT has advanced our understanding of many aspects of prokaryotic cell biology, from morphogenesis to subcellular compartmentalization and from metabolism to complex interspecies interactions. In this Review, we highlight how ECT has provided structural and mechanistic insights into the physiology of bacteria and archaea and discuss prospects for the future.
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Registered trials
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