ArticleScientific reports2016
In vivo and in vitro infection dynamics of honey bee viruses.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
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Who cites it
69 citing papers in PubMed, 120 citations in OpenAlex.
- Virus specific impacts on honey bee flight performance are mediated by the octopamine pathway.bioRxiv : the preprint server for biology · 2026Article
- Quantitation of cytopathic honey bee viruses using the viral plaque assay method.The Journal of general virology · 2026Article
- Patterns of viral prevalence and load show independent circulation of some honey bee viruses in wild bees.Scientific reports · 2026Article
- Caucasian and Egyptian chitosan/propolis nanocomposites inhibit deformed wing virus in Apis mellifera L. cell lines.Scientific reports · 2026Article
- Inapparent virus infections differentially affect honey bee flight.Science advances · 2025Article
- Mechanical transfer of honey bee (Hymenoptera: Apidae) virus sequences to wax by worker traffic and aerosolization.Journal of insect science (Online) · 2025Article
- Gut-binding peptides as potential tools to reduce virus binding to honey bee gut surface proteins.Applied and environmental microbiology · 2025Article
- Acute bee paralysis virus regulation of microRNA expression dynamics in the insect host (Frontiers in cellular and infection microbiology · 2025Article
- A novel antibody treatment reduces deformed wing virus loads in the western honey bee (mSphere · 2024Article
- Israeli Acute Paralysis Virus Is an Emerging Pathogen Contributing to Brood Disease ofViruses · 2024Article
- Mechanisms of Pathogen and Pesticide Resistance in Honey Bees.Physiology (Bethesda, Md.) · 2024Review
- Varroa destructor shapes the unique viral landscapes of the honey bee populations of the Azores archipelago.PLoS pathogens · 2024Article
- Article
- The effect of Israeli acute paralysis virus infection on honey bee brood care behavior.Scientific reports · 2024Article
- Consequences of microsporidian prior exposure for virus infection outcomes and bumble bee host health.Oecologia · 2023Article
- Review
- ThePathogens (Basel, Switzerland) · 2023Article
- Can egg yolk antibodies terminate the CSBV infection in apiculture?Virus research · 2023Review
- CRISPR-induced DNA reorganization for multiplexed nucleic acid detection.Nature communications · 2023Article
- Using the Honey Bee (Apis mellifera L.) Cell Line AmE-711 to Evaluate Insecticide Toxicity.Environmental toxicology and chemistry · 2023Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The honey bee (Apis mellifera) is commonly infected by multiple viruses. We developed an experimental system for the study of such mixed viral infections in newly emerged honey bees and in the cell line AmE-711, derived from honey bee embryos. When inoculating a mixture of iflavirids [sacbrood bee virus (SBV), deformed wing virus (DWV)] and dicistrovirids [Israeli acute paralysis virus (IAPV), black queen cell virus (BQCV)] in both live bee and cell culture assays, IAPV replicated to higher levels than other viruses despite the fact that SBV was the major component of the inoculum mixture. When a different virus mix composed mainly of the dicistrovirid Kashmir bee virus (KBV) was tested in cell culture, the outcome was a rapid increase in KBV but not IAPV. We also sequenced the complete genome of an isolate of DWV that covertly infects the AmE-711 cell line, and found that this virus does not prevent IAPV and KBV from accumulating to high levels and causing cytopathic effects. These results indicate that different mechanisms of virus-host interaction affect virus dynamics, including complex virus-virus interactions, superinfections, specific virus saturation limits in cells and virus specialization for different cell types.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.