Evidence map›Paper›PMID 26923108›Full record

ArticleMagnetic resonance in medicine2017

Volumetric multislice gagCEST imaging of articular cartilage: Optimization and comparison with T1rho.

Feliks Kogan, Brian A Hargreaves, Garry E Gold

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Magnetic resonance in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Advances in cartilage imaging techniques.Nature reviews. Rheumatology · 2026
    Review
  2. Early age-related changes to articular cartilage TOsteoarthritis and cartilage open · 2025
    Article
  3. Review
  4. Article
  5. A fast multislice sequence for 3D MRI-CEST pH imaging.Magnetic resonance in medicine · 2021
    Article
  6. Article
  7. Article
  8. Musculoskeletal MR Imaging Applications at Ultra-High (7T) Field Strength.Magnetic resonance imaging clinics of North America · 2021
    Review
  9. Rapid Knee MRI Acquisition and Analysis Techniques for Imaging Osteoarthritis.Journal of magnetic resonance imaging : JMRI · 2020
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Simultaneous bilateral-knee MR imaging.Magnetic resonance in medicine · 2018
    Article
  17. Applications of PET-MRI in musculoskeletal disease.Journal of magnetic resonance imaging : JMRI · 2018
    Review
  18. Review
  19. Review
  20. Potential of PET-MRI for imaging of non-oncologic musculoskeletal disease.Quantitative imaging in medicine and surgery · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Feliks KoganDepartment of Radiology, Stanford University, Stanford, California, USA.
Brian A HargreavesDepartment of Radiology, Stanford University, Stanford, California, USA.
Garry E GoldDepartment of Radiology, Stanford University, Stanford, California, USA.

Funding

X-RAY COMPATIBLE RF-COIL FOR MR IMAGINGP41RR009784 · NCRR · STANFORD UNIVERSITY · PI SKARE, STEFAN · 1995 to 2011
$15.0M
Rapid MRI for Evaluation of OsteoarthritisR01EB002524 · NIBIB · STANFORD UNIVERSITY · PI Akshay Chaudhari, Garry E Gold · 2003 to 2026
$10.1M
Quantitative 3D Diffusion and Relaxometry MRI of the KneeR01AR063643 · NIAMS · STANFORD UNIVERSITY · PI HARGREAVES, BRIAN ANDREW · 2013 to 2017
$2.5M
Advanced MR Imaging of Early OsteoarthritisK24AR062068 · NIAMS · STANFORD UNIVERSITY · PI GOLD, GARRY E · 2012 to 2022
$1.7M
NCRR NIH HHS P41 RR009784NIAMS NIH HHS K24 AR062068NIAMS NIH HHS R01 AR063643NIBIB NIH HHS R01 EB002524
6 · The paper itself

Abstract

purposeTo develop and optimize a multislice glycosaminoglycan (GAG) chemical exchange saturation transfer (GagCEST) sequence for volumetric imaging of articular cartilage, and to validate the sequence against T

methodsEx vivo experiments were used to observe the effect of the number of partitions and shot TR on signal-to-noise ratio and measured GagCEST

resultsEx vivo studies showed a higher average GagCEST

conclusionsWe demonstrated the feasibility and optimization of multislice GagCEST mapping of articular cartilage. Volumetric analysis and decreased scan times will help to advance the clinical utility of GagCEST imaging of articular cartilage. Magn Reson Med 77:1134-1141, 2017. © 2016 International Society for Magnetic Resonance in Medicine.

Indexed as

Signal Processing, Computer-AssistedAlgorithmsAnimalsAnkle JointCartilage, ArticularCattleGlycosaminoglycansHumansImage EnhancementImage Interpretation, Computer-AssistedIn Vitro TechniquesMagnetic Resonance ImagingMolecular ImagingReproducibility of ResultsSensitivity and SpecificityTissue DistributionGlycosaminoglycanscartilageGAGGagCESTosteoarthritis

Identifiers

PMID26923108
PMCPMC5002392

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.