Evidence map›Paper›PMID 26922879›Full record

Observational studyJournal of minimally invasive gynecology

Synthetic Graft Augmentation in Vaginal Prolapse Surgery: Long-Term Objective and Subjective Outcomes.

Isuzu Meyer, Gerald McGwin, Thomas A Swain, Mitchell D Alvarez, David R Ellington, Holly E Richter

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of minimally invasive gynecology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Surgical Updates in the Treatment of Pelvic Organ Prolapse.Rambam Maimonides medical journal · 2017
    Review
  6. Response to Letter to the Editor: Author's Reply.Journal of minimally invasive gynecology · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Isuzu MeyerDivision of Urogynecology and Pelvic Reconstructive Surgery, University of Alabama at Birmingham, Birmingham, AL. Electronic address: imeyer@uabmc.edu.
Gerald McGwinDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL.
Thomas A SwainDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, AL.
Mitchell D AlvarezDepartment of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL.
David R EllingtonDivision of Urogynecology and Pelvic Reconstructive Surgery, University of Alabama at Birmingham, Birmingham, AL.
Holly E RichterDivision of Urogynecology and Pelvic Reconstructive Surgery, University of Alabama at Birmingham, Birmingham, AL.

Funding

Mid Career Award in Patient Oriented Pelvic Floor ResearchK24DK068389 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RICHTER, HOLLY E · 2005 to 2014
$1.7M
NIDDK NIH HHS K24 DK068389
6 · The paper itself

Abstract

objectiveTo report long-term objectives and subjective outcomes in women who underwent prolapse surgery with a synthetic graft augmentation.

designRetrospective analysis (Canadian Task Force classification II-3).

settingUniversity hospital in the southeastern United States. PATIENTS: Women with symptomatic pelvic organ prolapse who underwent transvaginal graft augmentation using the Prolift mesh system between July 2006 and December 2008 for a minimum 5-year follow-up.

interventionsSubjects completed the Pelvic Floor Distress Inventory (PFDI-20), the Pelvic Floor Impact Questionnaire (PFIQ-7), the Pelvic Organ Prolapse/Urinary Incontinence Sexual Function Questionnaire (PISQ), and the Patient Satisfaction Questionnaire. Subjects also underwent postoperative physical examination with Pelvic Organ Prolapse Quantification (POP-Q) and vaginal pain/stricture assessment. Long-term postoperative findings were compared with preoperative baseline data. MEASUREMENTS AND MAIN

resultsOf 208 eligible subjects, 70 completed the questionnaires only, and 48 of these 70 provided both postoperative examination and questionnaire data. The mean duration of follow-up was 7.0 ± 0.7 years (range, 5.8-8.1 years). POP-Q measurements of Ba (point B anterior), Bp (B posterior), C (cervix), GH (genital hiatus), PB (perineal body), and overall pelvic organ prolapse stage were significantly improved (all p < .001 except for PB, p = .006). PFIQ-7 (total, Urinary Impact Questionnaire, and Pelvic Organ Prolapse Impact Questionnaire) and PFDI-20 (total, Urinary Distress Inventory, and Pelvic Organ Prolapse Distress Inventory) scores significantly improved (all p < .001). No differences were noted in the colorectal-anal subscales (Colorectal-Anal Impact Questionnaire and Colorectal-Anal Distress Inventory) and PISQ scores at >5-year follow-up (all p > .05). Satisfaction rates were 15.7% for not at all, 35.7% for somewhat, and 48.6% for completely satisfied. Complications included graft exposure (n = 3; 6%) and dyspareunia (n = 25; 36%).

conclusionWomen undergoing transvaginal prolapse surgery using a synthetic graft continue to have positive objective and subjective outcomes, leading to significantly improved quality of life at a minimum 5-year follow-up.

Indexed as

Surgical MeshDyspareuniaFemaleFollow-Up StudiesHumansMiddle AgedPatient SatisfactionPelvic FloorPelvic Organ ProlapsePostoperative CareQuality of LifeRetrospective StudiesSoutheastern United StatesSurveys and QuestionnairesTreatment OutcomeUrinary IncontinenceLong-term outcomesMeshPelvic organ prolapseProlapse surgeryTransvaginal mesh

Identifiers

PMID26922879
PMCPMC4851885

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.