Evidence map›Paper›PMID 26922795›Full record

Observational studyBMC nephrology2016

Prevalence of intradialytic hypotension, clinical symptoms and nursing interventions--a three-months, prospective study of 3818 haemodialysis sessions.

Johanna Kuipers, Jurjen K Oosterhuis, Wim P Krijnen, Judith J Dasselaar, Carlo A J M Gaillard, Ralf Westerhuis, Casper F M Franssen

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC nephrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Bradykinin BBMC nephrology · 2023
    Trial
  4. Article
  5. Article
  6. Article
  7. Article
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  9. Article
  10. Review
  11. Article
  12. Article
  13. Cerebrovascular Reactivity and Cerebral Ischemia During Chronic Hemodialysis.Hemodialysis international. International Symposium on Home Hemodialysis · 2025
    Article
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  15. Article
  16. Article
  17. Article
  18. Article
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  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Johanna KuipersDialysis Center Groningen, Hanzeplein 1, 9713, GZ, Groningen, The Netherlands. h.kuipers@dcg.nl.
Jurjen K OosterhuisDepartment of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Wim P KrijnenHanze University Groningen, University of Applied Sciences, Groningen, The Netherlands.
Judith J DasselaarDepartment of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Carlo A J M GaillardDepartment of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Ralf WesterhuisDialysis Center Groningen, Hanzeplein 1, 9713, GZ, Groningen, The Netherlands.
Casper F M FranssenDepartment of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Dialyse Centrum Groningen · NLUniversity Medical Center Groningen · NLUniversity of Groningen · NLHanze University of Applied Sciences · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntradialytic hypotension (IDH) is considered one of the most frequent complications of haemodialysis with an estimated prevalence of 20-50 %, but studies investigating its exact prevalence are scarce. A complicating factor is that several definitions of IDH are used. The goal of this study was, to assess the prevalence of IDH, primarily in reference to the European Best Practice Guideline (EBPG) on haemodynamic instability: A decrease in systolic blood pressure (SBP) ≥20 mmHg or in mean arterial pressure (MAP) ≥10 mmHg associated with a clinical event and the need for nursing intervention.

methodsDuring 3 months we prospectively collected haemodynamic data, clinical events, and nursing interventions of 3818 haemodialysis sessions from 124 prevalent patients who dialyzed with constant ultrafiltration rate and dialysate conductivity. Patients were considered as having frequent IDH if it occurred in >20 % of dialysis sessions.

resultsDecreases in SBP ≥20 mmHg or MAP ≥10 mmHg occurred in 77.7 %, clinical symptoms occurred in 21.4 %, and nursing interventions were performed in 8.5 % of dialysis sessions. Dialysis hypotension according to the full EBPG definition occurred in only 6.7 % of dialysis sessions. Eight percent of patients had frequent IDH.

conclusionsThe prevalence of IDH according to the EBPG definition is low. The dominant determinant of the EBPG definition was nursing intervention since this was the component with the lowest prevalence. IDH seems to be less common than indicated in the literature but a proper comparison with previous studies is complicated by the lack of a uniform definition.

Indexed as

AgedBlood PressureCohort StudiesDizzinessFatigueFemaleHumansHypotensionKidney Failure, ChronicMaleMiddle AgedMuscle CrampNauseaPrevalenceProspective StudiesRenal Dialysis

Identifiers

PMID26922795
PMCPMC4769826
OpenAlexW2286911405

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.