ArticleJournal of comparative physiology. B, Biochemical, systemic, and environmental physiology2016
Effective activation of antioxidant system by immune-relevant factors reversely correlates with apoptosis of Eisenia andrei coelomocytes.
Article in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 28 citations in OpenAlex.
- Dietary Ferrous Sulfate Enhances Resistance toPathogens (Basel, Switzerland) · 2025Article
- How does adulteration of wax foundation affect phenoloxidase and lysozyme activities as selected parameters of immunity inJournal of veterinary research · 2024Article
- Arginase Activity inInternational journal of molecular sciences · 2021Article
- In Vitro Interactions of TiONanomaterials (Basel, Switzerland) · 2021Article
- Enhanced Antioxidant and Cytotoxic Potentials of Lipopolysaccharides-InjectedPharmaceutics · 2020Article
- Mutual interactions of E. andrei earthworm and pathogens during the process of vermicomposting.Environmental science and pollution research international · 2020Article
- From Species to Regional and Local Specialization of Intestinal Macrophages.Frontiers in cell and developmental biology · 2020Review
- Construction of a cDNA library and preliminary analysis of the expressed sequence tags of the earthworm Eisenia fetida (Savigny, 1826).Molecular medicine reports · 2019Article
- Earthworm coelomocyte extracellular traps: structural and functional similarities with neutrophil NETs.Cell and tissue research · 2018Review
- Environmental pollutants, pathogens and immune system in earthworms.Environmental science and pollution research international · 2018Review
- Conservative Mechanisms of Extracellular Trap Formation by Annelida Eisenia andrei: Serine Protease Activity Requirement.PloS one · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oxidative stress is harmful to the microbes but also to the host, and may result in bystander damage or death. Because of this, respiratory burst triggered in phagocytes by pathogens is counteracted by production of antioxidative factors. The aim of this work was to examine effectiveness of the latter system in earthworms Eisenia andrei by induction of reactive oxygen species, lipofuscin and phenoloxidase by natural (LPS, zymosan, Micrococus luteus) and synthetic (phorbol ester, PMA) stimulants. The compounds impaired numbers, viability (increased apoptosis) and composition of coelomocytes, and triggered the antioxidant activity of catalase and selenium-dependent glutathione peroxidase. The natural pathogenic compounds, unlike PMA, strongly activated antioxidative responses that diminished cell apoptosis. Moreover, repeated exposure to the same or different pathogenic compounds did not induce respiratory burst exhausted phenotype showing that coelomocytes are constantly at bay to withstand numerous infections. The current study reveals importance and efficiency of the oxidative-antioxidative systems in annelids but also confirms its evolutionary conservatism and complexity even in lower taxa of the animal kingdom.
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