Trial reportJournal of evidence-based complementary & alternative medicine2017
A Traditional Mouthwash (Punica granatum var pleniflora) for Controlling Gingivitis of Diabetic Patients: A Double-Blind Randomized Controlled Clinical Trial.
Trial report in Journal of evidence-based complementary & alternative medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Treatment withCurrent pharmaceutical design · 2026Article
- Medicinal Plants Against Dental Caries: Research and Application of Their Antibacterial Properties.Plants (Basel, Switzerland) · 2025Review
- A Natural Approach to the Prevention and Treatment of Gingivitis and Periodontitis: A Review of Pomegranate's Bioactive Properties.Life (Basel, Switzerland) · 2024Review
- Herbal Composite Preparation and Investigating its Efficiency to Inhibit Biofilm Formation and Virulence Factors ofJournal of pharmacy & bioallied sciences · 2024Article
- Review
- Research impact in randomized controlled trials of diabetes: an altmetric approach.Journal of diabetes and metabolic disorders · 2023Article
- Evaluation of the topical gel and oral administration of Punica Granatum Var Pleniflora on oral mucositis induced by 5-Fluorouracil in golden hamsters.BMC complementary medicine and therapies · 2023Article
- Green Alternatives as Antimicrobial Agents in Mitigating Periodontal Diseases: A Narrative Review.Microorganisms · 2023Review
- Review
- A new glance at the role of traditional medicines in treatment of cancers.Journal of cancer research and clinical oncology · 2021Article
- Therapeutic Effects ofJournal of nutrition and metabolism · 2021Review
- Effects of Herbal Mouthwashes on Plaque and Inflammation Control for Patients with Gingivitis: A Systematic Review and Meta-Analysis of Randomised Controlled Trials.Evidence-based complementary and alternative medicine : eCAM · 2020Review
- Evaluation of Herbal Mouthwashes Containing Zataria Multiflora Boiss, Frankincense and Combination Therapy on Patients with Gingivitis: A Double-Blind, Randomized, Controlled, Clinical Trial.Galen medical journal · 2019Article
- Efficacy of Rose Oil Soft Capsules on Clinical Outcomes in Ulcerative Colitis: A Pilot Randomized, Double-Blinded, Placebo-Controlled Clinical Trial.Galen medical journal · 2019Article
- Medicinal plants for gingivitis: a review of clinical trials.Iranian journal of basic medical sciences · 2018Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study evaluates the safety and efficacy of Punica granatum var pleniflora mouthwash in treatment of diabetic gingivitis. In a double-blind randomized clinical trial 80 patients with diabetes mellitus and gingivitis were assigned to Golnaar and chlorhexidine 0.2% groups. After using mouthwashes for 2 weeks; participants underwent tooth scaling and the last visit was 2 weeks after scaling. The primary outcome measures were plaque, modified gingival and gingival bleeding indices, and pocket depth. Both interventions had significant improvement on all of the gingival and plaque indices (P < .001 for all indices). There were no significant differences between Golnaar and chlorhexidine in primary outcome measures except for modified gingival index for which Golnaar mouthwash had a superiority after 2 weeks when comparing with chlorhexidine (P = .039). Meanwhile, Golnaar mouthwash had no staining effect. Golnaar mouthwash is safe and effective in treatment of gingivitis in diabetic patients although further studies are recommended.
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