ArticleDrug and alcohol dependence2016
Pathways to adolescent sexual risk behaviors: Effects of prenatal cocaine exposure.
Article in Drug and alcohol dependence, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- Internal assets in low-income urban adolescents from 12 to 17 years: Gender variation.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2025Article
- Prenatal cocaine exposure and substance use disorder in emerging adulthood at age 21.Drug and alcohol dependence · 2023Article
- Substance use and individual assets in urban adolescents: Subgroups and correlates in emerging adulthood.Journal of adolescence · 2022Article
- Sex Differences in the Pathways from Exposure to Parental Fighting to Risky Sexual Activities Among Adolescents in Urban Neighborhoods.Maternal and child health journal · 2022Article
- Oscillatory Dynamics of Feedback Processing in Adolescents with Prenatal Cocaine Exposure.Developmental neuropsychology · 2019Article
- Profiles of individual assets and mental health symptoms in at-risk early adolescents.Journal of adolescence · 2019Article
- Prenatal cocaine exposure: Direct and indirect associations with 21-year-old offspring substance use and behavior problems.Drug and alcohol dependence · 2019Article
- Developmental trajectories of externalizing behavior from ages 4 to 12: Prenatal cocaine exposure and adolescent correlates.Drug and alcohol dependence · 2018Article
- Association of prenatal cocaine exposure, childhood maltreatment, and responses to stress in adolescence.Drug and alcohol dependence · 2017Article
- The association of prenatal cocaine exposure, externalizing behavior and adolescent substance use.Drug and alcohol dependence · 2017Article
- Prenatal cocaine exposure, early cannabis use, and risky sexual behavior at age 25.Neurotoxicology and teratologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundTo assess the impact of prenatal cocaine exposure (PCE) on adolescent sexual risk behaviors. Externalizing behavior, teen substance use, and early sexual intercourse were examined as pathways mediating the effects of PCE on sexual risk behaviors.
methodsAdolescents (N=364; 185 PCE, 179 non-cocaine exposure (NCE); 205 girls, 159 boys), primarily African-American and of low socioeconomic status, were prospectively enrolled in a longitudinal study at birth. Risky sexual behaviors were assessed at ages 15 and 17. Externalizing behavior at 12 years was assessed with the Youth Self-Report. Substance use, via self-report and biologic assays, and early (before age 15) sexual intercourse were assessed at age 15. Path analyses with the weighted least squares estimator with mean and variance adjustments were performed.
resultsThe final structural equation model-based path model, χ(2)=31.97 (df=27), p=.23, CFI=.99, TLI=.99, RMSEA=.021, WRMR=.695, indicated a direct effect of PCE on sexual risk behavior (β=.16, p=.02). Although PCE was related to greater externalizing behavior (β=.14, p=.009), which in turn, predicted early sexual intercourse (β=.16, p=.03), leading to sexual risk behavior (β=.44, p<.001), bootstrapping indicated a non-significant indirect effect (β=.01, p>.10). Substance use was correlated with early sexual intercourse (r=.60, p<.001) and predicted sexual risk behavior by age 17 (β=.31, p=.01).
conclusionsPrenatal cocaine exposure was related to more engagement in sexual risk behaviors, suggesting the importance of reducing substance use among pregnant women as a means of prevention of offspring substance use and sexual risk behavior.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.