Evidence map›Paper›PMID 26922172›Full record

ReviewCurrent neurology and neuroscience reports2016

Vaccines in Multiple Sclerosis.

Eric M L Williamson, Salim Chahin, Joseph R Berger

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Current neurology and neuroscience reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04300868 (Immunisation Status Against Major Communicable Diseases Preventable With Vaccines, and Safety of Vaccines, in a Cohort of MS Patients. An Italian Multicenter Study), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04300868 unknown statusnot on this mapstarted 2019, after this paper: background citation

Immunisation Status Against Major Communicable Diseases Preventable With Vaccines, and Safety of Vaccines, in a Cohort of MS Patients. An Italian Multicenter Study

TypeobservationalSponsorMonica UlivelliRan2019 to 2023Enrolled3,000ConditionsMultiple Sclerosis
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Pollution, Inflammation, and Vaccines: A Complex Crosstalk.International journal of environmental research and public health · 2021
    Review
  5. Article
  6. Article
  7. Article
  8. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2019
    Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Eric M L WilliamsonDepartment of Neurology, Division of Neuroimmunology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA, USA. ericwilliamsonmd@gmail.com.
Salim ChahinDepartment of Neurology, Division of Neuroimmunology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA, USA. salim.chahin@uphs.upenn.edu.
Joseph R BergerDepartment of Neurology, Division of Neuroimmunology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA, USA. joseph.berger@uphs.upenn.edu.
University of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccinations help prevent communicable disease. To be valuable, a vaccine's ability to prevent disease must exceed the risk of adverse effects from administration. Many vaccines present no risk of infection as they are comprised of killed or non-infectious components while other vaccines consist of live attenuated microorganisms which carry a potential risk of infection-particularly, in patients with compromised immunity. There are several unique considerations with respect to vaccination in the multiple sclerosis (MS) population. First, there has been concern that vaccination may trigger or aggravate the disease. Second, disease-modifying therapies (DMTs) employed in the treatment of MS may increase the risk of infectious complications from vaccines or alter their efficacy. Lastly, in some cases, vaccination strategies may be part of the treatment paradigm in attempts to avoid complications of therapy.

Indexed as

AnimalsChickenpoxHumansInfluenza, HumanMultiple SclerosisRisk FactorsVaccinationVaccinesVaccinesDisease-modifying therapyImmunityInfluenzaMultiple sclerosisVaccinationVaricella zoster

Identifiers

PMID26922172
OpenAlexW2278639014

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.