Evidence map›Paper›PMID 26922059›Full record

ArticleCardiovascular diabetology2016

Long-term mortality and incidence of cardiovascular diseases and type 2 diabetes in diabetic and nondiabetic obese patients undergoing gastric banding: a controlled study.

Antonio E Pontiroli, Ahmed S Zakaria, Ermanno Mantegazza, Alberto Morabito, Alessandro Saibene, Enrico Mozzi, Giancarlo Micheletto, LAGB10 working group

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Cardiovascular diabetology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

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  8. Prevention of Diabetes and Cardiovascular Disease in Obesity.International journal of molecular sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Antonio E PontiroliDipartimento di Scienze della Salute, Università degli Studi di Milano, Milan, Italy. antonio.pontiroli@unimi.it.
Ahmed S ZakariaOspedale San Paolo, Milan, Italy. zakariadrahmed@libero.it.
Ermanno MantegazzaOspedale San Paolo, Milan, Italy. ermanno.mantegazza@ao-sanpaolo.it.
Alberto MorabitoDipartimento di Scienze della Salute, Università degli Studi di Milano, Milan, Italy. alberto.morabito@gmail.com.
Alessandro SaibeneOspedale San Raffaele, Milan, Italy. saibene.alessandro@hsr.it.
Enrico MozziDipartimento di Scienze della Salute, Università degli Studi di Milano, Milan, Italy. enrico.mozzi@unimi.it.
Giancarlo MichelettoDipartimento di Scienze della Salute, Università degli Studi di Milano, Milan, Italy. giancarlo.micheletto@unimi.it.
LAGB10 working group
University of Milan · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITOspedale San Paolo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimAim of this retrospective study was to compare long-term mortality and incidence of new diseases [diabetes and cardiovascular (CV) disease] in morbidly obese diabetic and nondiabetic patients, undergoing gastric banding (LAGB) in comparison to medical treatment. PATIENTS AND

methodsMedical records of obese patients [body mass index (BMI) > 35 kg/m(2) undergoing LAGB (n = 385; 52 with diabetes) or medical treatment (controls, n = 681; 127 with diabetes), during the period 1995-2001 (visit 1)] were collected. Patients were matched for age, sex, BMI, and blood pressure. Identification codes of patients were entered in the Italian National Health System Lumbardy database, that contains life status, causes of death, as well as exemptions, drug prescriptions, and hospital admissions (proxies of diseases) from visit 1 to September 2012. Survival was compared across LAGB patients and matched controls using Kaplan-Meier plots adjusted Cox regression analyses.

resultsObservation period was 13.9 ± 1.87 (mean ± SD). Mortality rate was 2.6, 6.6, and 10.1 % in controls at 5, 10, and 15 years, respectively; mortality rate was 0.8, 2.5, and 3.1 % in LAGB patients at 5, 10, and 15 years, respectively. Compared to controls, surgery was associated with reduced mortality [HR 0.35, 95 % CI 0.19-0.65, p < 0.001 at univariate analysis, HR 0.41, 95 % CI 0.21-0.76, p < 0.005 at adjusted analysis], similar in diabetic [HR 0.34, 95 % CI 0.13-0.87, p = 0.025] and nondiabetic [HR 0.42, 95 % CI 0.19-0.97, p = 0.041] patients. Surgery was also associated with lower incidence of diabetes (15 vs 48 cases, p = 0.035) and CV diseases (52 vs 124 cases, p = 0.048), and of hospital admissions (88 vs 197, p = 0.04).

conclusionUp to 17 years, gastric banding is associated with reduced mortality in diabetic and nondiabetic patients, and with reduced incidence of diabetes and cardiovascular diseases.

Indexed as

AdultBariatric SurgeryBody Mass IndexCardiovascular DiseasesDiabetes Mellitus, Type 2FemaleHumansIncidenceItalyKaplan-Meier EstimateMaleMedical RecordsMiddle AgedMultivariate AnalysisObesityProportional Hazards Models

Identifiers

PMID26922059
PMCPMC4769489
OpenAlexW2289838898

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.