Evidence map›Paper›PMID 26920884›Full record

ReviewJournal of microbiology (Seoul, Korea)2016

The contribution of Aspergillus fumigatus stress responses to virulence and antifungal resistance.

Neil A Brown, Gustavo H Goldman

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of microbiology (Seoul, Korea), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 80 citations in OpenAlex.

  1. Review
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  12. Response of Fusarium oxysporum soil isolate to amphotericin B and fluconazole at the proteomic level.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  13. The Expanding Mycovirome ofJournal of fungi (Basel, Switzerland) · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Neil A BrownPlant Biology and Crop Science, Rothamsted Research, Harpenden, Hertfordshire, UK. neil.brown@rothamsted.ac.uk.
Gustavo H GoldmanFaculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, São Paulo, Brasil. ggoldman@usp.br.
Rothamsted Research · GBUniversidade de São Paulo · BR

Funding

Biotechnology and Biological Sciences Research Council BB/J/004383/1
6 · The paper itself

Abstract

Invasive aspergillosis has emerged as one of the most common life-threatening fungal disease of humans. The emergence of antifungal resistant pathogens represents a current and increasing threat to society. In turn, new strategies to combat fungal infection are urgently required. Fungal adaptations to stresses experienced within the human host are a prerequisite for the survival and virulence strategies of the pathogen. Here, we review the latest information on the signalling pathways in Aspergillus fumigatus that contribute to stress adaptations and virulence, while highlighting their potential as targets for the development of novel combinational antifungal therapies.

Indexed as

Adaptation, BiologicalAnimalsAntifungal AgentsAspergillosisAspergillus fumigatusDrug Resistance, FungalHost-Pathogen InteractionsHumansStress, PhysiologicalVirulenceAntifungal Agentsaspergillosiscell wall stressfungicide resistanceheat shockhypoxiaosmotic stressoxidative stress

Identifiers

PMID26920884
OpenAlexW2285751821

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.