Evidence map›Paper›PMID 26920872›Full record

ArticleJournal of cancer survivorship : research and practice2016

Complementary and alternative medicine use among US cancer survivors.

Gabriella M John, Dawn L Hershman, Laura Falci, Zaixing Shi, Wei-Yann Tsai, Heather Greenlee

Abstract read
In one paragraph

Article in Journal of cancer survivorship : research and practice, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Pooled it
  5. Guideline
  6. Pooled it
  7. Trial
  8. Trial
  9. Cancer pain.Nature reviews. Disease primers · 2026
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  11. Palliative Treatment and Traditional Medicine Among Patients with Cancer in Kumasi, Ghana: Needs for Patient Education.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
    Article
  12. Article
  13. Article
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  16. Evaluating the outcomes and patient experience of group and individual acupuncture in an NHS cancer care setting: a mixed-methods study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  17. Review
  18. Article
  19. Article
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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gabriella M JohnDepartment of Epidemiology, Mailman School of Public Health, Columbia University, 733 W 168th Street, room 733, New York, NY, 10032, USA.
Dawn L HershmanDepartment of Epidemiology, Mailman School of Public Health, Columbia University, 733 W 168th Street, room 733, New York, NY, 10032, USA.
Laura FalciDepartment of Epidemiology, Mailman School of Public Health, Columbia University, 733 W 168th Street, room 733, New York, NY, 10032, USA.
Zaixing ShiDepartment of Epidemiology, Mailman School of Public Health, Columbia University, 733 W 168th Street, room 733, New York, NY, 10032, USA.
Wei-Yann TsaiHerbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY, USA.
Heather GreenleeDepartment of Epidemiology, Mailman School of Public Health, Columbia University, 733 W 168th Street, room 733, New York, NY, 10032, USA. hg2120@cumc.columbia.edu.

Funding

Effects of Antioxidant Supplementation during Breast Cancer Adjuvant TherapyK23CA141052 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GREENLEE, HEATHER · 2009 to 2013
$753k
NCI NIH HHS K23 CA141052
6 · The paper itself

Abstract

purposeUS cancer survivors commonly use vitamins/minerals and complementary and alternative medicine (CAM). We compare use of vitamins/minerals and CAM between adult cancer survivors and cancer-free adults and estimate annual out-of-pocket expenses.

methodsData on self-reported vitamin/mineral and CAM use in the past 12 months from the cross-sectional 2012 US National Health Interview Survey were used to estimate prevalence of use and out-of-pocket expenditures. The cohort included adults with (n = 2977) and without (n = 30,551) a self-reported cancer diagnosis.

resultsApproximately 79 % of cancer survivors and 68 % of cancer-free adults reported using ≥1 vitamins/minerals and/or CAM modality in the past year. Compared to cancer-free adults, cancer survivors were more likely to report use of vitamin/minerals (75 vs. 61 %, P < 0.001), non-vitamin/mineral natural products (24 vs. 19 %, P < 0.001), manipulative and body-based therapies (19 vs. 17 %, P = 0.03), and alternative medical systems (5 vs. 4 %, P = 0.04). Adult cancer survivors and cancer-free adults spent an annual estimated $6.7 billion and $52 billion out-of-pocket, respectively, on vitamins/minerals and CAM. Survivors spent 60 % of the total on vitamins/minerals ($4 billion), 18 % ($1.2 billion) on non-vitamin/mineral natural products, and 7 % ($0.5 billion) on massage.

conclusionsCompared with cancer-free adults, a higher proportion of cancer survivors report vitamin/mineral and CAM use. Cancer survivors, who accounted for 6.9 % of the total population, accrued more than 11.4 % of the annual out-of-pocket costs on vitamins/minerals and CAM spent by US adults. IMPLICATIONS FOR CANCER SURVIVORS: Given the high use of vitamins/minerals and CAM in cancer survivors, studies are needed to analyze health outcomes and the cost/benefit ratio of such use.

Indexed as

AdolescentAdultAgedComplementary TherapiesCross-Sectional StudiesFemaleHealth ExpendituresHumansMaleMiddle AgedNeoplasmsSurvivorsUnited StatesYoung AdultCancerComplementary medicineComplementary therapiesHealthcare costsVitamins

Identifiers

PMID26920872
PMCPMC5001939

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.