Evidence map›Paper›PMID 26920681›Full record

ArticleThe journal of headache and pain2016

Impact of depression and anxiety on burden and management of episodic and chronic headaches - a cross-sectional multicentre study in eight Austrian headache centres.

Karin Zebenholzer, Anita Lechner, Gregor Broessner, Christian Lampl, Gernot Luthringshausen, Albert Wuschitz, Sonja-Maria Obmann, Klaus Berek, Christian Wöber

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in The journal of headache and pain, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 74 citations in OpenAlex.

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  18. Sleep disturbances in tension-type headache and migraine.Therapeutic advances in neurological disorders · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Karin ZebenholzerDepartment of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria. karin.zebenholzer@meduniwien.ac.at.
Anita LechnerDepartment of Neurology, Medical University of Graz, Graz, Austria. anita.lechner@klinikum-graz.at.
Gregor BroessnerDepartment of Neurology, Medical University of Innsbruck, Innsbruck, Austria. gregor.broessner@i-med.ac.at.
Christian LamplHeadache Centre Seilerstätte, Hospital Sisters of Charity Linz, Linz, Austria. christian.lampl@bhs.at.
Gernot LuthringshausenUniversity Clinic of Neurology, Christian-Doppler-Klinik Salzburg, Salzburg, Austria. g.luthringshausen@salk.at.
Albert WuschitzNeurological Office Vienna, Vienna, Austria. albertwuschitz@gmx.de.
Sonja-Maria ObmannDepartment of Neurology, Klinikum Klagenfurt, Klagenfurt, Austria. sonja-maria.obmann@kabeg.at.
Klaus BerekDepartment of Neurology, aö. BKH Kufstein, Kufstein, Austria. klaus.berek@bkh-kufstein.at.
Christian WöberDepartment of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria. christian.woeber@meduniwien.ac.at.
Medical University of Vienna · ATChristian Doppler Klinik · ATKlinikum Klagenfurt · ATMedical University of Graz · ATUniversität Innsbruck · ATUniversity of Applied Sciences Kufstein · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecurrent and especially chronic headaches are associated with psychiatric comorbidities such as depression and anxiety. Only few studies examined the impact of depression and anxiety on episodic (EH) and chronic headache (CH), and data for Austria are missing at all. Therefore, the aim of the present study was to assess the impact of depression and anxiety on burden and management of EH and CH in patients from eight Austrian headache centres.

methodsWe included 392 patients (84.1 % female, mean age 40.4 ± 14.0 years) who completed the Eurolight questionnaire. The treating physician recorded details about ever-before prophylactic medications. We used Hospital Anxiety and Depression Scale to assess depression and anxiety and compared patients with anxiety and/or depression to those without.

resultsDepression and anxiety were more common in CH than in EH (64 % vs. 41 %, p < 0.0001). Presence compared to absence of depression and anxiety increased the prevalence of poor or very poor quality of life from 0.7 % to 13.1 % in EH and from 3.6 % to 40.3 % in CH (p = 0.001; p < 0.0001). Depression and anxiety had a statistically significant impact on employment status and on variables related to the burden of headache such as reduced earnings, being less successful in career, or feeling less understood. Neither in EH nor in CH health care use and the ever-before use of prophylactic medication was correlated with anxiety and/or depression.

conclusionDepression and anxiety have a significant impact on quality of life and increase the burden in patients with EH and CH. Improved multidimensional treatment approaches are necessary to decrease disability on the personal, social and occupational level in these patients.

Indexed as

Cost of IllnessQuality of LifeAdultAnxietyAustriaComorbidityCross-Sectional StudiesDepressionFemaleHeadacheHeadache DisordersHumansMaleMiddle AgedAnxietyBurdenChronic headacheDepressionEpisodic headacheMedication overuse headacheMigrainePsychiatric comorbidityQuality of lifeTension-type headache

Identifiers

PMID26920681
PMCPMC4769233
OpenAlexW2286679128

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.