ReviewBiological research2016
Genetic variants associated with neurodegenerative Alzheimer disease in natural models.
Review in Biological research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 31 citations in OpenAlex.
- Diabetic retinopathy and Alzheimer's disease: Convergence of the unfolded protein response in neurodegeneration.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Review
- Exploring efficient and effective mammalian models for Alzheimer's disease.Frontiers in aging neuroscience · 2025Review
- Article
- In-silico structural analysis ofMolecular biology research communications · 2024Article
- Role of animal models in biomedical research: a review.Laboratory animal research · 2022Review
- Genome Sequencing Variations in theFrontiers in aging neuroscience · 2022Article
- Revelations About Aging and Disease from Unconventional Vertebrate Model Organisms.Annual review of genetics · 2021Review
- A Multivariate Assessment of Age-Related Cognitive Impairment inFrontiers in integrative neuroscience · 2021Article
- Disruption of Glucose Metabolism in AgedFrontiers in integrative neuroscience · 2021Article
- Establishment of a rat model with ageing insomnia induced by D-galactosef and para-chlorophenylalanine.Experimental and therapeutic medicine · 2020Article
- Postnatal Guinea Pig Brain Development, as Revealed by Magnetic Resonance and Diffusion Kurtosis Imaging.Brain sciences · 2020Article
- Evidence of Synaptic and Neurochemical Remodeling in the Retina of Aging Degus.Frontiers in neuroscience · 2020Article
- Strengths and Weaknesses of the Gray Mouse Lemur (Frontiers in pharmacology · 2019Review
- Amyloid β and free heme: bloody new insights into the pathogenesis of Alzheimer's disease.Neural regeneration research · 2018Review
- Alzheimer's disease: experimental models and reality.Acta neuropathologica · 2017Review
- Brain Transcriptome Sequencing of a Natural Model of Alzheimer's Disease.Frontiers in aging neuroscience · 2017Article
- Special series on trending themes in Neurobiology in Biological Research.Biological research · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of transgenic models for the study of neurodegenerative diseases has made valuable contributions to the field. However, some important limitations, including protein overexpression and general systemic compensation for the missing genes, has caused researchers to seek natural models that show the main biomarkers of neurodegenerative diseases during aging. Here we review some of these models-most of them rodents, focusing especially on the genetic variations in biomarkers for Alzheimer diseases, in order to explain their relationships with variants associated with the occurrence of the disease in humans.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.